Preparation of two-photon fluorescent probe and biological imaging application in cells-中国期刊网

摘要 Wereportonanoveldibenzothiophene-basedtwo-photonfluorescentprobeforselectivenuclearbioimaging,whichcontainsbilaterallysymmetricalpyridineringsconnectedbyacentralconjugated-bridgedibenzothiophene.Thisprobepossessesalargetwo-photonabsorptioncross-sectionof471GM,yieldsa25-foldenhancementofthefluorescencetitration,andastrongerphotostabilityfornucleilabelingthanexistingprobes.Thereal-timeobservationperiodisaminimumof1800sunderafemtosecondlaserexcitation,whichissignificantlylongerthanthatof40,6-diamidino-2-phenylindole.Theaboveresultsconfirmthatthisnovelmoleculeisasuitabletwo-photonfluorescentprobeforapplicationtonuclearbioimagingincells.

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Preparation of two-photon fluorescent probe and biological imaging application in cells

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Preparation of two-photon fluorescent probe and biological imaging application in cells

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