摘要
Intracerebralhaemorrhage(ICH),whichhasrapidattackandhighdeathrate,usuallyleadstobadoutcomes.Poorprognosisofthisdiseaseisprimarilyduetothedifficultyofearlydiscovery.Earlydetectionordiagnosiswouldsignificantlyreducetherateofdisabilityandmortality,andimprovetheprognosisofthepatients.Thepurposeofthispaperistotestifyelectricalimpedancechangeanddetectionofbraintissueaftercerebralischemicwithelectricalimpedancetomography.Inthisstudy,electricalimpedancetomography(EIT)wasappliedtodetecttheonsetofmodeledonrabbitsinrealtime,ICHmodelgroupwereinjectedcollagenaseintheCorpusStriatumwhilerabbitsincontrolgroupwereinjectedthesamevolumeofsalinewithcollagenase.Thesubsequentprocesswasmonitoredcontinuouslybysystemofelectricalimpedancetomography;therabbitsweresacrificedbyintravenousinjectionofoverdoseofhydrationchlorinealdehyde,andthentakenintobeingscannedbycomputedtomography(CT)witharesolutionof1mmwithin10minafterdeath.Afterthat,thebrainsoftherabbitsweretakenout,fixedandcutintoslicestodetectthechangesofbraintissue.Wefoundthatone-dimensionalimpedanceandtwo-dimensional(2D)imagesofelectricresistanceofbrainoftherabbitspretreatedwithcoilagenaseobviouslychangedafterinjectionandthehemorrhagecouldbefoundintheslicesofbrainandtherewerechangesinthemodelrabbitsgroupnotonlytheelectricresistancebutalsothebraintissues.quantitativeindexcan'tbeprovidedbydetectionofintracerebralhemorrhageAlthoughinrabbitswithelectricalimpedancetomography'satthisstage,cerebralhemorrhagecancausebrainelectricalimpedancecharactersofthechange,thecompletedexperimentssuggestthatelectricalimoedancetomograophr(EIT)maybecomeaneffectivetechniauetodetectICH.
出版日期
2017年02月12日(中国期刊网平台首次上网日期,不代表论文的发表时间)