摘要
Amodifiedpoly(ethyleneglycol)(PEG)hasbeendevelopedasthesolublepolymericsupportsforliquidphasesynthesisofnovelthioureaderivatives.Ineachstepofthesequence,thePEG-boundproductswereprecipitatedincoldEt2Oandtheunreactedmaterialsandby-productswereremovedbysimplefiltration.Theprogressofreaction,purityoftheisolationandthestructureofthePEG-boundproductswereeasilymonitoredbyTLC,IRand^1HNMRspectra.RepresentativethioureaderivativeswereobtainedinmoderateyieldswithexcellentpurityfromthismodifiedPEG-boundproductbythecleavagewith50%TFA/H2O.
出版日期
2002年02月12日(中国期刊网平台首次上网日期,不代表论文的发表时间)