摘要
ObjectiveThepurposeofthisstudy-wsatoinvestigatetheclinicalefficacyandsideef-fectsoffluoxetineinthetreatmentofobsessivecompulsivedisorder,Methods36patientswithobsessivecompulsivedisorderweretreatedbyfluoxetine(n=18)andclomipramine(n=18)andclomipramine(n=18),TheefficacywasmeasuredwithYALE-BrownObsessiveCompulsiveScale(Y-BOCS),MarksScaleforCompulsions,Phobias,ObsessionsandRituals(MSCPOR),andHamiltonDepressionScale(HAMD).ThesideeffectsweredeterminedbytheTreamentEmergentSymptomScale(TESS).ResultsThetherapeuticefficacyinfluoxetinegroupwassimilartothatinclomipramine(P>0.05).Howeverthesideeffectsoffluoxetinewerelighterthanclomipramine,CondusionTheresultsindicatetheatbothflu-oxetineandclomipramineiseffectiveinthetreatmentofobsessivecompulsivedisorder,butfluoxetineshowedmoreadvantagesforitsconventientadministrationandlowdaiydosageandthesideeffectsofitwerelight.
出版日期
2003年02月12日(中国期刊网平台首次上网日期,不代表论文的发表时间)