Effect of decoy-oligodeoxynucleotides on expression of inflammation mediators in pMΦ cells from rats-中国期刊网

摘要 Objective:Tostudytheeffectofdecoy-oligodeoxynucleotides(decoy-ODNs)indumbbellshapewiththeoligodeoxynucleotidesequencesimilartonuclearfactorkappaB(NF-κB)cis-elementsonexpressionofinflammationmediatorsinpMΦcellsfromrats.Methods:Withcarriersofcationicliposomes,decoy-ODNsweretransfectedintopMΦcellsofrats.Thentheinhibitingeffectsofthedecoy-ODNsontumornecrosisfactorα(TNFα),interleukin-6(IL-6)andIL-10wereanalyzed.Results:Decoy-ODNscoulddecreasetheexpressionofTNFαandIL-6indose-dependentfashionbuthadweakerinhibitingeffectonIL-10.Conclusions:Decoy-ODNstargetingNF-κBcandecreasetheexpressionofinflammatorymediatorsinpMΦcellsfromrats.

1San-Jun Chu;Zhao-Hua Zhang;Min Wang;Hai-Feng Xu. Effect of bevacizumab on the expression of fibrosis-related inflammatory mediators in ARPE-19 cells.眼科,2017-03.
2CHEN XiaoPing LIU Hong Wang Changyong GUO Qing FAN Ming. Isolation and clonal analysis of satellite cells from adult rats.生物医学工程,2001-02.
3Gui Shun-Ping,Zou Heng,Bai Yi,Liu Min,Wang Tao,Zhou Rong. Low Expression of FGF23 and Its Effect on Rats with Intrauterine Growth Retardation.医药卫生,2020-10.
4Jiang Chao;Liu Ping;Zhang Yun-yun;Zhang Qiu-juan;Huang Gao-min. Regulatory Effect of Electroacupuncture on Ceramide Galactosyltransferase Expression in Sciatic Nerve of Experimental Diabetic Rats.中医学,2014-01.
5赵强;吴同果;蒋作锋;陈国伟;林毅. Effect of β blockers on β3-adrenoceptor mRNA Expression in the Rats with Chronic Heart Failure.心血管疾病,2007-01.
6柳惠图;王端顺;张鸿卿;薛绍白;游劲松;杜春英;王晓良. THE EFFECT OF db-cAMP ON THE GENE EXPRESSION OF CALMODULIN AND CYTOSKELETON IN THE TRANSFORMED CELLS.肿瘤,1992-01.
7赵飞骏;吴移谋;刘双全;张晓红;余敏君. The Construction of the Eukaryotic Expression Vector of Glycerophosphodiester Phosphodiesterase Gene from Treponema pallidum and its Expression in Hela Cells.皮肤病学与性病学,2005-01.
8刘雷;裴福兴;唐康来;许建中;李起鸿. Expression and effect of Caspase-3 in neurons after tractive spinal cord injury in rats.临床医学,2005-04.
9朱锦宇;黄耀添;朱庆生;吕荣. Expression of adenovirus-mediated neurotrophin-3 gene in Schwann cells of sciatic nerve in rats.临床医学,2003-02.
10CAO Xianying;LI Shipu;DAI Honglian;DONG Changyuan. The Effect of Nano-apatite on the Expression of Telomerase Gene of Human Hepatocellular Carcinoma Cells.材料科学与工程,2005-01.

Effect of decoy-oligodeoxynucleotides on expression of inflammation mediators in pMΦ cells from rats

来源期刊

相关推荐

同分类资源更多

相关关键词

Effect of decoy-oligodeoxynucleotides on expression of inflammation mediators in pMΦ cells from rats

来源期刊

相关推荐

同分类资源 更多

相关关键词

同分类资源更多