摘要
摘要目的探讨右美托咪啶预防七氟醚麻醉小儿苏醒期躁动的临床效果.方法选取８４例小儿疝气手术患者,随机分为实验组和对照组两组,每组４２例.手术患儿均采用七氟醚诱导插管全麻.实验组泵入右美托咪啶１μg/kg??h,对照组患者泵入等量生理盐水,观察比较两组苏醒期躁动发生率和不良反应.结果实验组躁动率为７．２％,对照组躁动率为５２．４％(P＜０．０５),差异有统计学意义.实验组不良反应率为３１．０％,对照组为２６．２％(P＞０．０５),差异无统计学意义.结论七氟醚麻醉小儿手术中使用右美托咪啶可减少其苏醒期躁动发生率,右美托咪啶可安全有效地用于预防七氟醚麻醉小儿的苏醒期躁动且不良反应少.关键词右美托咪啶;小儿;七氟醚;苏醒期躁动AbstractObjectiveTostudytherightsupportingthedexmedetomidineorganismpreventionpediatricawakeningperiodsevofluraneanesthesiaclinicaleffectofagＧitation．Methods８４ASAⅠ－Ⅱchildrenwererandomlydividedinto２groupsexperimentalgroup(n＝４２)andcontrolgroup(n＝４２)．AftergeneralanesthesiainducＧtionandintubation,childreninexperimentalgroupwereintravenousinfusedwith１μg/kg??hdexmedetomidine,childrenincontrolgroupwereintravenousinfusedwiththesamevolumesofnormasaline,comparetheincidenceofmergenceagitationandadversereactionbetween２groups．ResultsInexperimentalgrouptheagitationratewas７．２％,inthecontrolgrouptheratewas５２．４％(P＜０．０５),thereissignificantdifferencebetween２groups．Adversereactionratewas３１．０％inexperimentalgroup,whilethecontrolgroupwas２６．２％(P＞０．０５),thereisnosignificantdifferencebetween２groups．ConclusionDexmedetomidinecansafelyandeffectivelyreducetherateofemergenceagitationinchildrenundersevofluraneanesthesiawithfewadversereactionDexmedetomidinecanbeusedtopreventtheemergeceagitationinchildrenundersevofluraneanesthesia．KeywordsDexmedetomidine;Children;Sevoflurane;Emergenceagitation中图分类号R７２６文献标识码B文章编号１００８－６３１５(２０１５)１２－０６６７－０１
出版日期
2015年12月22日（中国期刊网平台首次上网日期，不代表论文的发表时间）
