首页 > 《中国保健营养》 > 2019年2期 > 纳米碳技术在腹腔镜下子宫内膜癌术中寻找前哨淋巴结的临床研究

纳米碳技术在腹腔镜下子宫内膜癌术中寻找前哨淋巴结的临床研究

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DOI 54k8om0y4k/2585509

作者付小萌郭静姜娟（通讯作者）

机构地区（哈尔滨工业大学附属哈尔滨市第一医院妇一科黑龙江哈尔滨 150010）【摘要】目的：本研究目的是分析子宫内膜癌前哨淋巴结（Sentinel LymphNode, SLN）在子宫内膜癌精准治疗中的意义。方法：选取2016 年7 月1 日至2018 年12 月31 日于哈尔滨市第一医院收治的26例子宫内膜癌患者，所有患者采用宫颈注射纳米碳，先行SLN 切除再行腹腔镜下系统性淋巴结切除，对所有切除的淋巴结均行苏木素-伊（Hematoxylin-eosin, HE）染色的常规病理检测。应用SPSS21.0 软件进行统计分析，计数资料采用χ2 检验或Fisher 确切概率法，并行一致性Kappa 检验。P<0.05 认为差异有统计学意义。结果：1 子宫内膜癌SLN 检出率为100%，双侧均检出SLN 占92.3%（24/26），仅单侧检出SLN 占7.7%（2/26，左侧2 例），准确性为100%，假阴性率为0，阴性预测值为100%。2 26 例子宫内膜癌患者共切除SLN 164 枚，占切除总淋巴结的26.1%（164/628），平均切除SLN 6.47 枚/人，平均切除SLN 比NSLN 少11.86枚/人。3 子宫内膜癌SLN 分布为闭孔区占53.2%（87/164），髂外区占23.7%（38/164）。结论：1、纳米碳是很好的子宫内膜癌SLN的示踪剂，宫颈部位注射示踪剂是显示SLN 较好的注射途径。2、子宫内膜癌SLN 主要位于闭孔区和髂外区。3 、在子宫内膜癌患者中行SLN 识别技术是安全、可行的。【

出处《中国保健营养》 2019年2期

关键词前哨淋巴结子宫内膜癌检出率中图分类号R276 文献标识码A 文章编号1004-7484（2019）02-0137-02 A clinical study on the search of Sentinel lymph nodes in laparoscopic endometrial carcinoma with nanocarbon Fu Xiaomeng Guo Jing Jiangjuan (Harbin First Hospital Affiliated to Harbin Institute of Technology Women's Section 1 Harbin Heilongjiang 150010) AbstractObjective The purpose of this study was to analyze the significance of Sentinel lymph node(SLN) in the accurate treatment of endometrial carcinoma.Methods 26 patients with endometrial cancer were selected from July 1 2016 to December 31 2018 at Harbin No. 1 Hospital. All patients were treated with cervical injection of Nano carbon SLN was removed first and laparoscopic systemic lymph node resection was performed. All removed lymph nodes were routinely pathologically examined for Sumusu(HE) staining. SPSS21 .0 software is used for statistical analysis. The counting data is measured using the < UNK> 2 test or the Fisher exact probability

分类 [医药卫生][公共卫生与预防医学]

出版日期 2019年02月12日（中国期刊网平台首次上网日期，不代表论文的发表时间）

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中国保健营养

中国保健营养

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前哨淋巴结子宫内膜癌检出率中图分类号R276 文献标识码A 文章编号1004-7484（2019）02-0137-02 A clinical study on the search of Sentinel lymph nodes in laparoscopic endometrial carcinoma with nanocarbon Fu Xiaomeng Guo Jing Jiangjuan (Harbin First Hospital Affiliated to Harbin Institute of Technology Women's Section 1 Harbin Heilongjiang 150010) AbstractObjective The purpose of this study was to analyze the significance of Sentinel lymph node(SLN) in the accurate treatment of endometrial carcinoma.Methods 26 patients with endometrial cancer were selected from July 1 2016 to December 31 2018 at Harbin No. 1 Hospital. All patients were treated with cervical injection of Nano carbon SLN was removed first and laparoscopic systemic lymph node resection was performed. All removed lymph nodes were routinely pathologically examined for Sumusu(HE) staining. SPSS21 .0 software is used for statistical analysis. The counting data is measured using the < UNK> 2 test or the Fisher exact probability

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