摘要
摘要目的探讨Ranibizumab(雷珠单抗)玻璃体腔内注射联合Ex-press青光眼引流钉植入治疗新生血管性青光眼的围手术期护理要点.方法给予16例新生血管性青光眼患者(16眼)先行Ranibizumab(雷珠单抗)玻璃体腔内注药术,待虹膜新生血管消退或消失后,行Ex-press青光眼引流钉植入术,充分做好围手术期的各项护理工作.结果16例患者顺利完成手术.玻璃体注药术后3~7d,14例患者虹膜新生血管完全消退.术后平均眼压1mo13.16±2.82mmHg,3mo13.90±2.50mmHg,6mo14.50±1.45mmHg,12mo15.62±1.55mmHg,术后1、3、6、12mo眼压与术前相比有统计学意义(P<0.05).2例视力有提高,14例患者视力保持原水平.完全成功8例,部分成功5例,手术成功率81%.结论Ranibizumab玻璃体腔内注射可迅速消退虹膜新生血管,联合Express青光眼引流钉植入术,创伤小,降低眼内出血的风险,是治疗新生血管性青光眼的有效术式,做好围手术期的的护理工作是确保手术疗效的关键.关键词雷珠单抗;Ex-press植入术;新生血管性青光眼;围手术期护理PerioperativenursingcareofRanibizumabcombinedwithEx-pressminiatureglaucomadeviceimplantationforneovascularglaucomaAbstractAbstractobjectiveToevaluatethekeypointsinperioperativenursingcareofRanibizumabcombinedwithEx-pressminiatureglaucomadeviceimplantaGtionforneovascularglaucoma.METHODS16eyesof16patientswithneovascularglaucoma(NVG)weretreatedbyintravitreousinjectionofRanibizumabcomGbinedwithEx-pressminiatureglaucomadeviceimplantationafteratrophyofirisneovascularization.RESULTSOperationwassuccessfullyperformedin16paGtients.Irisneovascularizationwascompletelyregressedduring3-7dafterinjectionin14eyes.MeanIOPafterEx-presssurgerywas(13.16±2.82),(13.90±2.50),(14.50±1.45),(15.62±1.55)mmHgrespectivelyatmonth1,month3,month6,andmonth12aftersurgery.TheIOPof8eyeswerelessthan21mmHgwithoutanydrugsandof5eyeswith1-2kindsofanti-glaucomadrugsafterEx-presssurgery.CONCLUSIONIntravitreousinjectionofRanibizumabcouldsignificantlyreducetheregressionofirisneovascularization.RanibizumabcombinedwithEx-pressminiatureglaucomadeviceimplantationcanstableloweringIOPandhasfewercomplicationsforneurovascularglaucoma.ComprehensivenursingcareduringperioperativeperiodisthekeytoensuretheclinicaleffectoftreatmKeenyt.wordsRanibizumab;Ex-pressimplant;neovascularglaucoma;perioperativenursing中图分类号R453文献标识码B文章编号1008-6315(2015)12-0008-020
机构地区
彭明珠王继红刘二华王科蕾江苏省无锡市中医医院江苏无锡214001作者简介:彭明珠,工作单位:江苏省无锡市中医医院手术室,职称:主管护师.通讯作者:王继红,工作单位:江苏省无锡市中医医院眼科,职称:副主任医师,医学博士.刘二华,工作单位:湖南省衡阳市南华大学附属第一医院眼科,职称:主任医师,教授.王科蕾,工作单位:江苏省无锡市中医医院眼科,职称:住院医师.
出版日期
2015年12月22日(中国期刊网平台首次上网日期,不代表论文的发表时间)