摘要
摘要目的探讨舒芬太尼术后镇痛对结核性脓胸手术患者肺功能的影响.方法７９例手术治疗的结核性脓胸患者术后均应用静脉自控镇痛方法,随机分为观察组４１例与对照组３８例,观察组术后给予舒芬太尼镇痛,对照组术后给予吗啡镇痛,比较两组视觉模拟疼痛(VAS)评分、肺功能、应激因子、不良反应.结果１．VAS评分术后４h、８h、１２h、２４h,观察组VAS评分均明显低于对照组(t＝２．９１５~５．８９３,P＜０．０５);２．肺功能术后２h,观察组用力肺活量(FVC)、第一次用力呼气量(FEV１)、最大呼气中段流量(MMEF)明显高于对照组(t＝５．３６４~８．１２６,P＜０．０５);３．应激反应镇痛泵拔除时,观察组皮质醇(Cor)、C反应蛋白(CRP)均明显低于对照组(t＝３．２２３~５．１２３,P＜０．０５);４．不良反应观察组瘙痒、恶心、呕吐等不良应用明显低于对照组(x２＝４．３５２~４．４５４,P＜０．０５).结论舒芬太尼术后镇痛有利于抑制应激反应,改善肺功能,降低不良反应,是一种安全有效的镇痛药物.关键词结核性脓胸;舒芬太尼;术后镇痛;肺功能;应激反应TheimpactofsufentanilpostoperativeanalgesiaonlungfunctioninpatientswithtuberculouspyothoraxoperationsAbstractobjectiveTostudyeffectofsufentanilpostoperativeanalgesiaonlungfunctioninpatientswithtuberculouspyothoraxoperations．Methods７９caＧsespatientswithtuberculouspyothoraxbyintravenouscontrolledanalgesiaweredividedintoobservationgroup(４１cases)andcontrolgroup(３８cases),observaＧtiongrouppostoperativelygivensufentanilanalgesia,controlgroupgivenmorphineanalgesia,VAS,lungfunction,stressfactor,adversereactionswerecomparedbetweentwogroups．Result１．VASscoreafteroperation４h,８h,１２h,２４h,theobservationgroupVASscoresweresignificantlythanthatcontrolgroup(t(t＝２．９１５~５．８９３,P＜０．０５);２．Lungfunctionafteroperation２h,observationgroupFVC,FEV１,MMEFwassignificantlyhigherthanthatofcontrolgroup(t＝５．３６４~８．１２６,P＜０．０５);３．Stressresponseanalgesiapumppullout,observationgroupCRP,Corweresignificantlylowerthanthecontrolgroup(t＝３．２２３~５．１２３,P＜０．０５);４．Adversereactionsobservationgrouppruritus,nausea,vomitingetcadverseapplicationsignificantlylowerthanthecontrolgroup(x２＝４．３５２~４．４５４,KPey＜w０o．r０d５s)．ConclusionSufentanilpostoperativeanalgesiahelptorestrainstressreaction,improvelungfunction,reduceadversereactions．Tuberculouspyothorax;Sufentanil;Postoperativeanalgesia;Lungfunction;Stressresponse中图分类号R６１４文献标识码B文章编号１００８－６３１５(２０１５)１２－０３９２－０２
出版日期
2015年12月22日（中国期刊网平台首次上网日期，不代表论文的发表时间）
