摘要
Thepurposeofthisinvestigationistostudytheclinicalcharacteristicsofinfectionsbycommunity-acquiredmethicillin-resistantStaphylococcusaureus(MRSA)andtheconditionofantibioticsresistanceoftheclinicalisolatesinordertoguidefortherationaluseofantibiotics.Withtheclinicalisolatesfromcasesofhospital-acquiredMRSAatthesameperiodascontro|s,theclinicalcharacteristicsofinfectionsbycommunity-acquiredMRSAinHangzhouareaandthepatternofnon-β-lactamaseantibioticsresistanceweredeterminedinthisstudy.Itwasfoundthattheaverageageofpatientswithcommunity-acquiredMRSAinfectionswas30.89+13.3,incomparisonwiththoseofthehospital-acquiredpatientsof56.0+11.8,appearingtobeyoungerthanthoseofthelatter,andtheformershowingnoanybasicillness.Bothoftheformerandthelatterweresensitivetovancomycin(100%vs100%),andtheyhadthesamedegreesofsensitivitytorifampicin,fosfomycin,andSTM/TMP(86.8%vs88.1%,P>0.05;81.6%vs82.9%,P>0.05;and52.6%vs61.9%,P>0.05,respectively).Theformerwasmoresensitivetonetimycin,chndamycin,erythromycinandminocyclinethanthoseofthelatter(73.7%vs50.5%,P<0.01;60.5%vs45.7%,P<0.05;28.9%vs11.4%,P<0.01;and81.6%vs58.6%,P<0.01respectively).Meanwhile,theincidenceofmulti-resistantstrainofisolatesintheformerwassignificantlylowerthanthatofthelatter(31.6%vs81.0%,P<0.01).Inconclusion,itappearsthatthestrainsofclinicalisolatesisolatedfrompatientswiththecommunity-acquiredMRSAinfectionsshowdifferentclinicalcharacteristicsandantimicrobialsusceptibilityincomparisonwiththoseofthehospital-acquiredcasesofinfection,andthisnecessitatesanalterationinthechemotherapyofinfectionssuspectedtobecausedbycommunity-acquiredMRSA.
出版日期
2004年02月12日（中国期刊网平台首次上网日期，不代表论文的发表时间）
