摘要
摘要目的探讨沙美特罗/替卡松粉吸入剂联合噻托溴铵粉雾剂治疗支气管哮喘的临床疗效及不良反应.方法选择９０例在本院接受支气管哮喘治疗的患者随机分为实验组和对照组,每组各４５例.对照组采用常规治疗,实验组在常规治疗基础上给予沙美特罗/替卡松粉吸入剂联合噻托溴铵粉雾剂治疗.观察比较两组临床疗效及相关指标.结果实验组总有效率、显效率分别为９７．７８％(４４/４５)和６２．２２％(２８/４５),明显高于对照组８０．０％(３６/４５)和３３．３３％(１５/４５),差异具有统计学意义(P＜０．０５).与治疗前相比,两组治疗后PEF、FEV１均升高,嗜酸性粒细胞和IgE含量均降低,但实验组PEF、FEV１升高幅度和嗜酸性粒细胞、IgE含量降低幅度均高于对照组,差异有统计学意义(P＜０．０５).结论沙美特罗/替卡松粉吸入剂联合噻托溴铵粉雾剂治疗支气管哮喘具有较好的临床疗效,能明显缓解症状,不良反应轻,值得在临床上推广使用.关键词沙美特罗替卡松粉吸入剂;噻托溴铵;粉雾剂;支气管哮喘;疗效AbstractObjectiveToexaminetheclinicalcurativeeffectandsideeffectsofSalmeterolXinafoateandFluticasonePropionatepowderforInhalationcombinedwithThiＧamethoxamJoebromidepowdermistonbronchialasthma．Methods９０patientswithbronchialasthmawererandomlydividedintotheexperimentalgroupandthecontrolgroup,eachgrouphad４５patients．TheexperimentalgroupweretreatedwiththiamethoxambromidepowderatomizationtreatmentofmistonthebasisofconventionaltreatＧment,thecontrolgroupweretreatedbyroutinetherapy．Themutualindexandefficacyoftwogroupsofpatientswerecompared．ResultsTotaleffectiverateandefficiencyintheexperimentalgroupweresignificantlybetterthanthatinthecontrolgroup(９７．７８％vs．８０．０％and６２．２２％vs．３３．３３％,respectively,P＜０．０５)．PEFandFEV１wereinＧcreasedwhileeosinophilsnumberandserumIgElevelswerereducedinbothgroups,whiletherangeofincreasingandreducingpercentageinexperimentalgrouparesignifiＧcantlyhigherthanthatincontrolgroup(P＜０．０５)．ConclusionSalmeterolXinafoateandFluticasonePropionatepowderforInhalationcombinedwithThiamethoxamJoebroＧmidepKoewydewrormdisstisworthytousedinclinic,asit??sgoodeffectstoimprovesymptomsandlesssideeffectsonbronchialasthma．SalmeterolXinafoateandFluticasonePropionatepowderforInhalationThiamethoxamJoebromide;Pinkmist;Bronchialasthma;curativeeffect中图分类号R５６２．２文献标识码B文章编号１００８－６３１５(２０１５)１２－０５７２－０１
出版日期
2015年12月22日（中国期刊网平台首次上网日期，不代表论文的发表时间）
