Synthesis and biological evaluation of ethyl 6-alkoxy-7-phenyl-4-hydroxy-3-quinolinecarboxylates against Eimeria tenella

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摘要 Aseriesofethyl6-alkoxy-7-phenyl-4-hydroxy-3-quinolinecarboxylatesweredesignedandsynthesized.Theirstructureswereconfirmedby~1HNMR,~(13)CNMR,IRandHRMS.ThebiologicalactivitieswereprimarilyevaluatedagainstEimeriatenellaaccordingtoAnticoccidialIndex(ACI)methodinvivo.Theresultsshowedthatcompounds5e,5fand5iexhibitedanticoccidialactivitiesagainstE.tenellaat27mgkg~(-1).
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出版日期 2010年04月14日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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