低分子肝素联合激素、环磷酰胺治疗难治性肾病综合征的临床疗效研究

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摘要   【摘 要】目的:探究低分子肝素联合激素、环磷酰胺治疗难治性肾病综合征疗效。方法:选择 86例难治性肾病综合征患者,随机分成 A组与 B组。观察两组治疗后临床相关指标情况及治疗效果。结果:治疗 1月后, B组肌酐、尿素氮、 24h尿蛋白定量水平均优于 A组( P<0.05) ;B组治疗总有效率为 95.35%,显著高于 A组的 69.77%,两组存在较大差异( P<0.05)。结论:低分子肝素联合激素、环磷酰胺治疗难治性肾病综合征疗效较为显著,值得临床广泛推广。    【关键词】低分子肝素 ;激素 ;环磷酰胺 ;难治性肾病综合征    [Abstract] Objective: To explore the effect of low molecular weight heparin combined with hormone and cyclophosphamide in the treatment of refractory nephrotic syndrome. Methods: 86 patients with refractory nephrotic syndrome were randomly divided into group A and group B. To observe the clinical indicators and therapeutic effect of the two groups. Results: after one month of treatment, the quantitative levels of creatinine, urea nitrogen and 24-hour urine protein in group B were better than those in group A (P < 0.05); the total effective rate in group B was 95.35%, significantly higher than 69.77% in group A, and there was a significant difference between the two groups (P < 0.05). Conclusion: low molecular weight heparin combined with hormone and cyclophosphamide is more effective in the treatment of refractory nephrotic syndrome, which is worth popularizing.
出处 《世界复合医学》 2020年1期
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出版日期 2020年04月27日(中国期刊网平台首次上网日期,不代表论文的发表时间)