胃肠道间质瘤的临床病理诊断及鉴别诊断评价

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摘要   【摘要】目的:对胃肠道间质瘤的临床病理诊断及鉴别判断进行探究。方法:从本院在 2015年 1月到 2018年 11月间收治的胃肠道间质瘤患者中进行抽样,对其中 16例患者的临床资料进行回顾性分析,探究患者的临床病理诊断与鉴别诊断情况。结果:在本次选取的 16例患者中,其中 10例为梭形细胞、 2例为上皮样细胞、 4例 2种细胞混合型,免疫组化免中的 CD117、 CD34、 SMA与 S-100蛋白的阳性率分别别为 93.75%、 75%、 18.75%、 12.5%。结论:在目前对胃肠道间质瘤患者进行病理诊断与鉴别诊断的过程中,在充分研读 HE染片后,免疫组化 CD117、 CD34是病理诊断的重要依据,同时再结合 SMA与 S-100,能够更好的提升诊断准确率,具有较高的推广价值。    【关键词】胃肠道间质瘤 ;病理诊断 ;鉴别判断  [Abstract] Objective: To investigate the clinicopathological diagnosis and differential diagnosis of gastrointestinal stromal tumors. Methods: from January 2015 to November 2018, 16 patients with gastrointestinal stromal tumor were sampled, and the clinical data were analyzed retrospectively to explore the clinical pathological diagnosis and differential diagnosis. Results: of the 16 patients, 10 were spindle cells, 2 were epithelioid cells and 4 were mixed cells. The positive rates of CD117, CD34, SMA and S-100 were 93.75%, 75%, 18.75% and 12.5% respectively. Conclusion: in the process of pathological diagnosis and differential diagnosis of gastrointestinal stromal tumor patients, after fully studying HE staining, immunohistochemistry CD117 and CD34 are the important basis of pathological diagnosis. At the same time, combining SMA and S-100, it can better improve the accuracy of diagnosis and has a high promotion value.
出处 《世界复合医学》 2020年1期
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出版日期 2020年04月27日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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