摘要
【摘要】目的 探讨美托洛尔应用于急性心梗早期溶栓中的疗效及安全性影响。方法 将 2018年 3月～ 2019年 9月于因急性心肌梗死（ AMI）于我院就诊的患者 81例纳入研究并随机分组，对照组采用常规治疗，观察组加用美托洛尔， 28天为一疗程。比较两组治疗前后心电图 QRS积分改善情况，比较两组患者 28天内再梗死率及死亡率情况，比较两组疗效差异。结果 治疗后，观察组心电图 QRS积分更低（ P<0.05）；观察组患者再梗死率及死亡率均降低，差异有统计学意义（ P<0.05）；对照组总有效率 72.50%（ 29/40），观察组为 92.68%（ 38/41），高于对照组（ P<0.05）。结论 美托洛尔在急性心梗早期溶栓中有较高的应用价值，可提高疗效，并改善预后，值得推广。
【关键词】美托洛尔；急性心梗；溶栓；安全性分析
[Abstract] Objective To explore the efficacy and safety of metoprolol in early thrombolysis of acute myocardial infarction. Methods from March 2018 to September 2019, 81 patients with acute myocardial infarction (AMI) in our hospital were included in the study and randomly divided into two groups. The control group was treated with conventional therapy, and the observation group was treated with metoprolol for 28 days. The improvement of QRS score of ECG before and after treatment was compared between the two groups, and the reinfarction rate and mortality within 28 days were compared between the two groups. Results after treatment, the QRS score of ECG in the observation group was lower (P < 0.05); the reinfarction rate and mortality rate in the observation group were lower (P < 0.05); the total effective rate in the control group was 72.50% (29 / 40), 92.68% (38 / 41) in the observation group, higher than that in the control group (P < 0.05). Conclusion metoprolol has a high application value in early thrombolysis of AMI. It can improve the curative effect and prognosis, and it is worth popularizing.
出版日期
2020年04月27日（中国期刊网平台首次上网日期，不代表论文的发表时间）
