摘要
【摘要】 目的：分析复方甘草酸苷联合还原型谷胱甘肽对酒精性肝硬化患者肝功能的影响效果。方法：选择笔者所在医院 2017年 1月 -2019年 12月收治 198例酒精性肝硬化患者，随机分成两组，对照组 99例使用还原型谷胱甘肽治疗，研究组 99例在对照组基础上增加使用复方甘草酸苷治疗，对两组患者肝功能及肝纤维化指标进行比较。结果：研究组患者治疗后 AST、 ALT、 GGT、 TBIL指标均低于对照组，差异均有统计学意义（ P<0.05） ;研究组患者治疗后 PCⅢ、 IV-C、 HA指标分别为（ 102.78±29.87）、（ 62.60±14.41）、（ 77.40±20.04） μg/L，各项指标均低于对照组，差异均有统计学意义（ P<0.05）。结论：复方甘草酸苷联合还原型谷胱甘肽治疗酒精性肝硬化患者，可改善患者肝功能及肝纤维化指标，能有效促进临床症状好转，临床上值得推广使用。
【关键词】 复方甘草酸苷 ; 还原型谷胱甘肽 ; 酒精性肝硬化 ; 肝功能
[Abstract] Objective: to analyze the effect of Compound Glycyrrhizin Combined with reduced glutathione on liver function in patients with alcoholic cirrhosis. Methods: 198 patients with alcoholic cirrhosis were randomly divided into two groups: the control group (99 cases) were treated with reduced glutathione and the study group (99 cases) were treated with Compound Glycyrrhizin on the basis of the control group. The liver function and liver fibrosis indexes of the two groups were compared. Results: after treatment, AST, alt, GGT and TBIL in the study group were lower than those in the control group (P < 0.05), while PC Ⅲ, IV-C and HA in the study group were (102.78 ± 29.87), (62.60 ± 14.41), (77.40 ± 20.04) μ g / L, respectively, and all indexes were lower than those in the control group (P < 0.05). Conclusion: Compound Glycyrrhizin Combined with reduced glutathione in the treatment of alcoholic liver cirrhosis can improve the liver function and liver fibrosis index of patients, and can effectively promote the improvement of clinical symptoms, which is worth popularizing.
出版日期
2020年06月12日（中国期刊网平台首次上网日期，不代表论文的发表时间）
