摘要
【摘要】 目的 探讨甲状腺全切手术与半切手术治疗甲状腺癌的疗效和安全。方法 选择 2019年 1月～ 2020年 6月来我院就诊的 66例甲状腺癌患者， 采用随机法分为观察组及对照组， 各 33例。对照组患者采用半切手术， 观察组患者采用全切手术。比较两组患者手术切口、手术出血量、手术时间、住院时间 ;甲状腺功能减退、手足麻木、低血钙、喉返神经损伤发生情况。结果 观察组患者的手术切口为（ 6.2±0.8） cm， 长于对照组的（ 5.4±0.6） cm， 差异具有统计学意义 （ t=4.596， P<0.05）。观察组患者的手术出血量为（ 91.2±20.6） ml， 多于对照组的（ 59.6±11.5） ml， 差异具有统计学意义 （ t=7.694， P<0.05）。观察组患者的手术时间为（ 113.5±21.6） min， 长于对照组的（ 62.5±19.2） min， 差异具有统计学意义（ t=10.138， P<0.05）。观察组患者的住院时间为（ 7.0±1.5） d， 长于对照组的（ 6.1±1.8） d， 差异具有统计学意义（ t=2.207， P<0.05）。观察组患者的甲状腺功能减退、手足麻木、低血钙发生率均高于对照组， 差异均具有统计学意义（ χ2=3.995、 4.258、 4.243， P<0.05） ;两组患者的喉返神经损伤发生率比较， 差异无统计学意义（ χ2=0.216， P>0.05）。结论 采用全切手术进行甲状腺癌的治疗， 其暂时性甲状腺功能低下表现较明显， 但病灶切除更为彻底， 复发率低。全切手术不会造成喉返神经损伤， 虽然有其他并发症， 但可得到控制， 具有安全性， 可以推广应用。
【关键词】 甲状腺全切手术 ;半切手术 ;甲状腺癌 ;甲状腺功能减退
[Abstract] Objective To investigate the efficacy and safety of total and partial thyroidectomy in the treatment of thyroid cancer. Methods 66 patients with thyroid cancer from January 2019 to June 2020 in our hospital were randomly divided into observation group and control group, 33 cases in each group. The control group was treated with half cut operation, while the observation group was treated with total resection. The incision, bleeding volume, operation time, hospitalization time, hypothyroidism, numbness of hands and feet, hypocalcemia and recurrent laryngeal nerve injury were compared between the two groups. Results the incision of the observation group was (6.2 ± 0.8) cm, which was longer than that of the control group (5.4 ± 0.6) cm, the difference was statistically significant (t = 4.596, P < 0.05). The bleeding volume of the observation group was (91.2 ± 20.6) ml, which was more than that of the control group (59.6 ± 11.5) ml, the difference was statistically significant (t = 7.694, P < 0.05). The operation time of the observation group was (113.5 ± 21.6) min, which was longer than that of the control group (62.5 ± 19.2) min, the difference was statistically significant (t = 10.138, P < 0.05). The hospitalization time of the observation group was (7.0 ± 1.5) d, which was longer than that of the control group (6.1 ± 1.8) d, the difference was statistically significant (t = 2.207, P < 0.05). The incidence of hypothyroidism, numbness of hands and feet, hypocalcemia in the observation group were higher than those in the control group, the differences were statistically significant (χ 2 = 3.995, 4.258, 4.243, P < 0.05); there was no significant difference in the incidence of recurrent laryngeal nerve injury between the two groups (χ 2 = 0.216, P > 0.05). Conclusion total resection of thyroid cancer for the treatment of temporary hypothyroidism is more obvious, but the lesion resection is more thorough, the recurrence rate is low. Although there are other complications, it can be controlled and safe, so it can be widely used.
出版日期
2020年09月12日（中国期刊网平台首次上网日期，不代表论文的发表时间）
