拉贝洛尔、硫酸镁联合硝苯地平治疗妊高症患者的疗效观察及安全性分析

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摘要    [摘要 ]目的:分析拉贝洛尔、硫酸镁联合硝苯地平治疗妊高症的效果及安全性。方法:对照组与观察组均由 40例患者组成,对照组实施拉贝洛尔联合硫酸镁治疗,观察组实施拉贝洛尔、硫酸镁联合硝苯地平片治疗,对比两组实验室指标、不良反应率。结果:在治疗后的血压和 24h尿蛋白定量水平比较中,观察组的水平较治疗前和对照组,均改善更加显著, P<0.05;观察组不良反应发生率较对照组降低 15.00%, P<0.05。结论:妊高症患者在疾病治疗的过程中联合应用拉贝洛尔、硫酸镁联合硝苯地平片,可快速恢复血压指标,将 24h尿蛋白定量控制在合理范围内,药物使用后安全性得到认可,因此可进行推广普及。     [关键词 ]拉贝洛尔,硫酸镁,硝苯地平,妊高症,安全性    [Abstract] Objective: to analyze the efficacy and safety of labetalol, magnesium sulfate combined with nifedipine in the treatment of pregnancy induced hypertension. Methods: the control group and the observation group were composed of 40 patients. The control group was treated with labetalol combined with magnesium sulfate, and the observation group was treated with labetalol and magnesium sulfate combined with nifedipine tablets. The laboratory indexes and adverse reaction rates of the two groups were compared. Results: in the comparison of blood pressure and 24-hour urinary protein quantitative level after treatment, the level of observation group was more significantly improved than that before treatment and control group, P < 0.05; the incidence of adverse reactions in observation group was 15.00% lower than that in control group, P < 0.05. Conclusion: the combination of labetalol, magnesium sulfate and nifedipine tablets in the treatment of pregnancy induced hypertension can quickly recover blood pressure index, control the 24-hour urine protein in a reasonable range, and the safety of drug use is recognized, so it can be popularized.
作者 苍柏
出处 《中华医学信息导报》 2020年9期
关键词
出版日期 2020年09月12日(中国期刊网平台首次上网日期,不代表论文的发表时间)