摘要
【摘要】 目的 分析血清 C反应蛋白（ CRP）检验在病毒性心肌炎诊断中的作用。方法 40例病毒性心肌炎患者作为观察组， 另选同期接受健康体检的 40例健康者作为对照组。观察组患者于入院后第 1天、第 3天、第 7天、第 14天空腹时抽取静脉血标本， 通过免疫比浊法对血清 CRP水平进行检测。对照组于体检时通过免疫比浊法检测血清 CRP水平。分析对比观察组患者不同时间段与对照组 CRP水平 ;轻中度、重度病毒性心肌炎患者 CRP水平。结果 观察组入院第 1天 CRP水平为（ 24.66±5.34） mg/L， 入院第 3天为（ 16.87±3.24） mg/L， 入院第 7天为（ 8.45±1.23） mg/L， 入院第 14天为（ 8.72±1.20） mg/L;对照组体检时 CRP水平为（ 8.53±1.27） mg/L。观察组入院第 1天、第 3天 CRP水平处于最高水平， 均明显高于对照组， 差异具有统计学意义（ t=18.5856、 15.1571， P=0.0000、 0.0000<0.05） ;经治疗后观察组 CRP水平逐渐下降， 入院第 7天、第 14天 CRP水平恢复正常水平， 与对照组对比， 差异无统计学意义（ t=0.2862、 06877， P=0.7755、 0.4937>0.05）。重度病毒性心肌炎患者 CRP水平（ 24.62±4.20） mg/L高于轻中度病毒性心肌炎患者的（ 19.24±3.62） mg/L， 差异具有统计学意义（ t=4.3507， P=0.0000<0.05）。结论 在病毒性心肌炎诊断中 CRP可作为早期诊断参照指标， 为临床医生提供更多诊断依据， 判断患者病毒性心肌炎程度， 提高诊断准确率， 尽早使患者得到治疗， 避免患者病情延误。
【关键词】 血清 C反应蛋白检验 ;病毒性心肌炎 ;免疫比浊法 ;诊断价值
[Abstract] Objective To analyze the role of serum C-reactive protein (CRP) in the diagnosis of viral myocarditis. Methods 40 patients with viral myocarditis were selected as the observation group, and 40 healthy people who received physical examination at the same time were selected as the control group. In the observation group, venous blood samples were taken on the first day, third day, seventh day and fourteenth day after admission. In the control group, the serum CRP level was detected by immunoturbidimetric method. The CRP levels of patients in the observation group at different time periods and the control group, and the CRP levels of patients with mild to moderate and severe viral myocarditis were analyzed and compared. Results the CRP level of the observation group on the first day of admission was (24.66 ± 5.34) mg / L, the third day was (16.87 ± 3.24) mg / L, the seventh day was (8.45 ± 1.23) mg / L, the 14th day was (8.72 ± 1.20) mg / L; in the control group, the CRP level was (8.53 ± 1.27) mg / L. The CRP level of the observation group was at the highest level on the first and third day of admission, which was significantly higher than that of the control group (t = 18.5856, 15.1571, P = 0.0000, 0.0000 < 0.05); After treatment, the CRP level of the observation group gradually decreased, and it returned to normal level on the 7th and 14th day after admission, and the difference was not statistically significant (t = 0.2862, 06877, P = 0.7755, 0.4937 > 0.05). The level of CRP in patients with severe viral myocarditis (24.62 ± 4.20) mg / l was higher than that in patients with mild to moderate viral myocarditis (19.24 ± 3.62) mg / L, and the difference was statistically significant (t = 4.3507, P = 0.0000 < 0.05). Conclusion in the diagnosis of viral myocarditis, CRP can be used as a reference index for early diagnosis, provide more diagnostic basis for clinicians, judge the degree of viral myocarditis, improve the diagnostic accuracy, make patients get treatment as soon as possible, and avoid the delay of patients' condition.
出版日期
2020年09月14日（中国期刊网平台首次上网日期，不代表论文的发表时间）
