摘要
[摘要 ]目的：研究分析喹硫平配伍帕罗西汀治疗双向情感障碍的疗效，并观察其不良反应。方法：随机选取患有双向情感障碍，且进入本院进行治疗的患者 80例，将 80例患者随机分为两组，每组各 40例，一组为研究组，给予喹硫平配伍帕罗西汀进行治疗，另一组为对照组，单独给予帕罗西汀进行治疗。观察两组患者的治愈情况及不良反应发生率。结果：研究组整体的治愈率高于对照组，不良反应发生率低于对照组，在治愈率和不良反应发生率上，两组有显著性差异， P<0.05。结论：喹硫平配伍帕罗西汀对双向情感障碍的疗效高于单独使用帕罗西汀，同时不良反应低，值得在临床上推广使用。
[关键词 ]喹硫平；帕罗西汀；双向情感障碍
[Abstract] Objective: To study and analyze the efficacy of quetiapine combined with paroxetine in the treatment of bi-directional affective disorder, and observe its adverse reactions. Methods: 80 patients with bi-directional affective disorder were randomly selected and treated in our hospital. 80 patients were randomly divided into two groups, 40 in each group. One group was the study group, which was treated with quetiapine combined with paroxetine, the other group was the control group, which was treated with paroxetine alone. The cure and the incidence of adverse reactions were observed. Results: the overall cure rate of the study group was higher than that of the control group, and the incidence of adverse reactions was lower than that of the control group. There was a significant difference in the cure rate and the incidence of adverse reactions between the two groups (P < 0.05). Conclusion: the efficacy of quetiapine combined with paroxetine in the treatment of bi-directional affective disorder is higher than that of paroxetine alone, and the adverse reactions are low, which is worthy of clinical application.
出版日期
2020年09月14日（中国期刊网平台首次上网日期，不代表论文的发表时间）
