摘要
TheRamanspectrafromleukemiccellline(HL60)andnormalhumanperipheralbloodmononuclearceils(PBMCs)areobtainedbyconfocalmicro-Ramanspectroscopyusingnear-infraredlaser(785nm)excitation.Thescanningrangeisfrom500to2000cm-1.ThetwoaverageRamanspectraofnormalPBMCsandcarcinomacellshavecleardifferencesbecausetheirstructureandamountofnucleicacid,protein,andothermajormoleculesarechanged.Thespectraarealsocomparedandanalyzedbyprincipalcomponentanalysis(PCA)todemonstratethetwodistinctclustersofnormalandtransformedcells.Thesensitivityofthistechniqueforidentifyingtransformedcellsis100%.更多还原
出版日期
2008年12月22日(中国期刊网平台首次上网日期,不代表论文的发表时间)