简介：　　【摘要】 目的 探讨分析 3.0 T磁共振动态增强扫描在垂体微腺瘤中的表现特征及应用价值。方法 系统回顾分析 38例临床明确诊断垂体微腺瘤患者， 均使用 3.0 T磁共振进行平扫、动态增强扫描以及延迟扫描， 以总结 3.0 T磁共振动态增强扫描在垂体微腺瘤中的表现特征及应用价值。结果 38例垂体微腺瘤经平扫检出 25例， 检出率为 65.8%， 经动态增强扫描检出 36例， 检出率为 94.7%， 其中 11例为磁共振平扫正常患者。动态增强扫描表现为正常垂体组织的强化信号高于肿瘤区， 并且二者之间存在较为清晰的边界。延时扫描， 垂体微腺瘤组织可有缓慢强化的表现， 其中 7例延时扫描见肿瘤区信号增强， 但仍低于正常垂体组织， 4例延时扫描肿瘤区信号高于正常垂体组织。结论 3.0 T磁共振动态增强扫描在垂体微腺瘤的诊断中具有特征性的检出信号， 同时能够显著的提高垂体微腺瘤的检出率， 提高诊断的可靠性， 采用磁共振动态增强扫描可作为诊断垂体微腺瘤的常规检查手段。  　　【关键词】 磁共振成像；动态增强扫描；垂体微腺瘤  　 [Abstract] Objective To explore the characteristics and application value of dynamic contrast-enhanced MRI in pituitary microadenoma. Methods 38 patients with pituitary microadenoma were analyzed systematically. All patients were scanned with 3.0T MR, including plain scan, dynamic contrast-enhanced scan and delayed scan. Results 25 of 38 pituitary microadenomas were detected by plain scan, the detection rate was 65.8%, 36 by dynamic contrast-enhanced scan, the detection rate was 94.7%, 11 of them were normal patients. Dynamic enhanced scanning showed that the signal intensity of normal pituitary tissue was higher than that of tumor area, and there was a clear boundary between them. Delayed scanning showed that pituitary microadenoma tissue could be enhanced slowly. In 7 cases, delayed scanning showed signal enhancement in tumor area, but it was still lower than that in normal pituitary tissue, and in 4 cases, delayed scanning signal in tumor area was higher than that in normal pituitary tissue. Conclusion 3.0T dynamic contrast-enhanced MRI has the characteristic detection signal in the diagnosis of pituitary microadenoma, and can significantly improve the detection rate of pituitary microadenoma, improve the reliability of diagnosis. Using dynamic contrast-enhanced MRI scan can be used as a regular inspection method for the diagnosis of pituitary microadenoma.

简介：　　 [摘要 ] 目的 探讨 3.0T磁共振弹力成像在继发性颅内肿瘤中的应用价值。 方法 选取我院 2018年 1月～ 2019年 1月收治的脑肿瘤患者 87例，均为脑转移瘤，将所有患者分别通过 3.0T磁共振弹力成像和普通 MRI进行诊断，然后手术或者活检进行病理诊断，比较 3.0T磁共振与普通 MRI对于颅内转移瘤检测的准确性。 结果 3.0T磁共振弹力成像与病理诊断的相符率明显高于普通 MRI，其对于恶性级别的判断也优于普通 MRI（ P < 0.05）。 结论 3.0T磁共振弹力成像可以对继发性脑肿瘤做出准确的判定，对于指导临床治疗具有重要作用。  　　 [关键词 ] 3.0T磁共振弹力成像；继发性颅内肿瘤；应用价值  　　 [Abstract] Objective To investigate the application value of 3.0T elastic magnetic resonance imaging in diagnosis of secondary intracranial tumors. Methods Selected 87 patients with brain tumors in our hospital from January 2018to January 2019 and they were all of brain metastases. All patients diagnosed through 3.0T elastic magnetic resonance imaging and normal MRI， and then by surgery or biopsy for pathological diagnosis. Compared brain metastases detection accuracy of 3.0T elastic magnetic resonance imaging with normal MRI. Results 3.0T elastic magnetic resonance imaging matched pathological diagnosis significantly higher than normal MRI， and the differentiation of malignancy level was also better than normal MRI （ P < 0.05） . Conclusion 3.0T elastic magnetic resonance imaging can stretch secondary brain tumors make an accurate judgment for the clinical treatment and has an important role.  　　 [Key words] 3.0T elastic magnetic resonance imaging； Secondary intracranial tumors； Application value  　　颅内肿瘤是临床上常见的疾病，随着近些年诊断及影像技术的提高以及社会环境的影响、人们生活习惯和饮食结构的变化，颅内肿瘤的发病率呈逐年上升趋势。颅内肿瘤主要分为原发性颅内肿瘤和继发性颅内肿瘤，原发性颅内肿瘤主要是指来源于颅骨、脑膜、血管、垂体、颅神经、脑实质和残留的胚胎组织的肿瘤，继发性颅内肿瘤是指身体其他部位的恶性肿瘤转移或侵入颅内形成的转移瘤，多来源于肺和乳腺肿瘤，约占颅内肿瘤的 6%～ 7%，严重威胁肿瘤患者的生命和生活质量。目前对继发性颅内肿瘤的准确定性、定位、定数并确定恶性程度对于指导临床手术治疗具有重要的意义。本研究探讨了 3.0T磁共振弹力成像技术应用于颅内转移瘤的应用分析，现报道如下。  　　 1 资料与方法  　　 1.1 一般资料  　　选取我院 2018年 1月～ 2019年 1月收治的脑肿瘤术前患者 87例，其中男 43例，女 44例，年龄 23～ 65岁，平均（ 42.5±5.5）岁，主要以颅内高压、肢体运动障碍和感觉障碍就诊，所有肿瘤均经手术病理证实，所有病例均有其他部位的原发肿瘤，其中肺癌 32例，乳腺癌 40例，其他 15例。排除所有炎症、良性占位病变、原发性脑肿瘤患者及其他原因导致肢体运动及感觉障碍的患者。  　　 1.2 方法  　　患者取常规体位，使用 Siemens公司 3.0T MRI成像系统，常规行轴位、矢状面和冠状位扫描，记录患者的诊断结果，然后再使用弹力成像技术进行分析，所有的图像均经过两名放射科医师（从事体部磁共振诊断 5年以上）分别阅片，定性诊断意见不一致时请高一级医师阅片，得出最后结论；手术切除标本进行组织病理及免疫组化分析，根据癌细胞的分化程度及转移程度确定恶性程度，确定其为转移瘤是根据病理检查的癌细胞的类型与原发病灶的癌细胞类型相符。  　　 1.3 统计学分析  　　研究的所有数据均通过 SPSS 17.0进行处理，计量数据使用（ x±s）表示，组间比较采用 t检验；计数资料使用百分比表示，组间比较采用 χ2检验， P<0.05为差异有统计学意义。

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