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简介：DNAcondensationisanimportantprocessinmanyfieldsincludinglifesciences,polymerphysics,andappliedtechnology.Inthenucleus,DNAiscondensedintochromosomes.Inpolymerphysics,DNAistreatedasasemi-flexiblemoleculeandapolyelectrolyte.Manyagents,includingmulti-valentcations,surfactants,andneutralpoorsolvents,cancauseDNAcondensation,alsoreferredtoascoil–globuletransition.Moreover,DNAcondensationhasbeenusedforextractionandgenedeliveryinappliedtechnology.ManyphysicaltheorieshavebeenpresentedtoelucidatethemechanismunderlyingDNAcondensation,includingthecounterioncorrelationtheory,theelectrostaticzippertheory,andthehydrationforcetheory.Recentlyseveralsingle-moleculestudieshavefocusedonDNAcondensation,sheddingnewlightonoldconcepts.Inthisdocument,themulti-fieldconceptsandtheoriesrelatedtoDNAcondensationareintroducedandclarifiedaswellastheadvancesandconsiderationsofsingle-moleculeDNAcondensationexperimentsareintroduced.

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简介：AdoublehelixmodelofchargetransportinDNAmoleculeisgivenandthetransmissionspectraoffourDNAsequencesareobtained.ThecalculatedresultsshowthatthetransmissioncharacteristicsofDNAarenotonlyrelatedtothelongitudinaltransportbutalsotothetransversetransportofmolecule.Theperiodicsequencewiththesamecompositionhasstrongerconductionability.Withtheincreasingofbasescomposition,theconductiveabilityreduces,buttheweightofθdirectionrisesinchargetransfer.

简介：由直接diagonalizing脱氧核糖核酸酸(DNA)的梯子模型的Hamiltonian分子，状态的密度被获得。DNA作为一个售票员表现，这被发现什么时候内部链跳跃比小两次intrachain不那样，DNA作为一个半导体表现。

简介：Chaosgamerepresentation(CGR)isaniterativemappingtechniquethatprocessessequencesofunits,suchasnucleotidesinaDNAsequenceoraminoacidsinaprotein,inordertodeterminethecoordinatesoftheirpositionsinacontinuousspace.Thisdistributionofpositionshastwofeatures:oneisunique,andtheotherissourcesequencethatcanberecoveredfromthecoordinatessothatthedistancebetweenpositionsmayserveasameasureofsimilaritybetweenthecorrespondingsequences.ACGR-walkmodelisproposedbasedonCGRcoordinatesfortheDNAsequences.TheCGRcoordinatesareconvertedintoatimeseries,andalong-memoryARFIMA(p,d,q)model,whereARFIMAstandsforautoregressivefractionallyintegratedmovingaverage,isintroducedintotheDNAsequenceanalysis.ThismodelisappliedtosimulatingrealCGR-walksequencedataoftengenomicsequences.Remarkablylong-rangecorrelationsareuncoveredinthedata,andtheresultsfromthesemodelsarereasonablyfittedwiththosefromtheARFIMA(p,d,q)model.

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简介：用常压气相沉积法镀膜制得的二氧化钛薄膜为催化剂，以紫外灯为光源，研究了亚甲基蓝的光催化降解。实验表明：镀膜时基片温度为２００℃；用铜线作为底物，在染料溶液中加Ｈ２Ｏ２，可提高光催化活性。更多还原

简介：Theground-stateandthermodynamicpropertiesofquantummixed-spinchainsof1/2-1/2-1-1and3/2-3/2-1-1areinvestigatedbyaquantumMonteCarlosimulationwiththeloop-clusteralgorithm.For1/2-1/2-1-1chain,wefindithastwophasesseparatedbyanenergy-gapvanishingpointintheground-state.For3/2-3/2-1-1chain,thenumericalresultsshowtwoenergy-gapvanishingpointsisolatedbydifferentphasesinitsground-state.Ourcalculationsindicatethatallthesegroundstatephasescanbeunderstoodbymeansofvalence-bond-solidpicture,andthethermodynamicbehavioratfinitetemperaturesiscontinuousasafunctionofparameterα=J2/J1.

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简介：1．河水总是向低处流，抛出的物体总会落向地面，这些现象说明，地球上的物体总是要受到________力的作用，该力的施力物体是______。

简介：TheDNA-dependentproteinkinasecatalyticsubunit(DNA-PKcs)playsamajorroleinDNAdamagesignalingandrepair,andisalsofrequentlyover-expressedintumormetastasis.WeusedisogeniccelllinesexpressingdifferentlevelsofDNA-PKcstoinvestigatetheroleofDNA-PKcsinmetastaticdevelopment.Interestingly,ourresultsshowedthatX-rayirradiationinducedthemetastasisofDNA-PKcspositive(M059K)butnotnegative(M059J)cells;however,genisteincouldsuppresstheradiation-inducedmetastaticpotentialofM059Kcells(Fig.1).Theconcretemechanismsunderlyingthisphenomenonwillbeinvestigatednextyear.

简介：Heavyionirradiationattractalargeinterestfortwoapplications:radiotherapyandspaceradiationprotectioninmannedspacemissions.ExposuretoheavyionsradiationresultsinmultipleeffectsthroughDNAdamageinduction.Single-cellgelelectrophoresisorcometassayisknownforitsabilitytodetectDNAdamageatthesinglecelllevelandhasbeenusedforyearstoassessDNAdamage.ItcandetectlowlevelsofDNAstrandbreaksinashorttime,justusingafewsamplecells.DNAdoublestrandbreaks(DSBs)aremeasuredattheneutralcometassaycondition;underthealkalinecometassayconditionbothDNAsinglestrandbreaks(SSBs)andpartDSBsaredetected.Thetwodimensionalcometassayisamodificationofthetwooriginalcometassay,cansimultaneouslydetectDNASSBsandDSBsinthesamehumanspermatozoa.

简介：2-(二硝基亚甲基)-4，5-咪唑烷二酮(1)是1998年首次报道的一个新化合物，是Latypov等在探索合成低感高能炸药1，1-二氨基-2，2-二硝基乙烯(FOX-7)的过程中得到的一个重要中间体，它去掉羰基开环即得FOX-7，

简介：In2014,theresearchersofTheoreticalPhysicsGroupatIMPhavecarriedouttheirresearchworkonnuclearphysics,heavyionphysicsandhadronphysics.Someimportantresultshavebeenobtained.Thethree-bodyforce(TBF)effectontheoff-shellbehavioroftheneutronandprotonmassoperatorsinasymmetricuclearmatterhasbeeninvestigatedwithintheframeworkoftheextendedBrueckner-Hartree-Fockapproach[1].Athighdensitieswellabovethenormalnuclearmatterdensity,theTBFisshowntoaffectsignificantlytheoff-shellehaviorofboththeprotonandneutronmassoperators.Thedensitydependenceofsymmetryenergyaroundtheuclearsaturationdensityhasbeenstudied[2].Anewapproachhasbeenproposedandappliedtodeterminetheymmetryenergycoefficientofheavynucleibasedontheavailableexperimentalnuclearmassesofheavynuclei.Theobtainedresultisadoptedtoanalyzethedensitydependenceofsymmetryenergyofnuclearmatteraroundtheaturationdensity.TheslopeparameteratthesaturationdensityisdeterminedtobeL=(50.515.5)MeV.

简介：AlterationsinDNArepair,cellcycle,andapoptoticpathwaysareoftenassociatedwithcancerriskandradiationsensitivity.IndividualswithreducedDNAdamageresponsefaceagreatersensitivitytomutagenchallenge.Interindividualvariabilityinmutagenorradiationsensitivityandincancersusceptibilitymayalsobetracedbacktopolymorphismsofgenesaffectinge.g.DNArepaircapacity[1].

简介：Amongthemanyspecialfactorsinthespaceenvironment,spaceradiationespeciallyhighenergyheavyionradiationiswidelyregardedasoneofthecrucialfactorsthathazardthehealthandsafetyofastronaut.Itiswellknownthatbiologicaleffectsofradiationaredependentonthelinear-energy-transfer(LET)oftheemergentbeam.HeavyionshavehighLETandcouldinducecomplexandclusteredDNAdamage,whichismoredifficulttoberepairedthanindividuallesionsandisevenirreparable.

简介：In2010,theBESCollaboration[1]foundaclearenhancementintheK0K0massdistributionintheJ=ψ!ηK0K0decay.SuchanenhancementisusuallyasignatureofanL=0resonancearoundthreshold,whichinthiscasewouldcorrespondstoanh1statewithquantumnumbersIG(JPC)=0??(1+??).Thish1statewaspredictedbytheChiralUnitarytheoryintheKKinteraction.Becauseoftheconversationlaw,thisstatecanonlydecaytoK0K0channel,andcanbestudiedefficientlyintheJ=ψ!ηK0K0decay.