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  • 简介:ANEWCERAMIDEFROMTHEMARINESPONGEBIEMNASP.¥ZhiZERG;LongMeiZENG;JingYuSU(DepartmentofChemistry,ZhongshanUniversity,Guangzhou,610...

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  • 简介:Marineorganismsaretheimportantsourceofthebioactivemetabolites.Anovelenolicsulfatedsterol,arenicolsterolA,hasbeenisolatedfromamarineannelidArenicolacristatacollectedinthecoastofMainlandofChina.ThestructurewaselucidatedusingallsortsofspectroscopicdataincludingESIMS,1Dand2DNMRetc.ThecytotoxicbioactivityofthissterolwasevaluatedbyMTTassay.Itcouldinhibitthegrowthofhumancervixcancercellline(Hela)andhumannon-smallcelllungcancercellline(NCI-h6)withIC50of(3.1+0.6)μg/mLand(7.6+0.8)μg/mL.

  • 标签: 细胞毒素 烯醇 硫酸盐 甾酮 有机体