简介: 【摘要】 目的 分析替诺福韦酯对核苷(酸)耐药的慢性乙型肝炎伴肝衰竭患者的临床效果。方法 60例对核苷(酸)耐药的慢性乙型肝炎伴肝衰竭患者, 随机分为对照组和观察组, 每组30例。对照组患者给予常规内科治疗, 观察组患者在对照组基础上给予富马酸替诺福韦二吡呋酯片治疗。观察比较两组患者乙肝病毒的脱氧核糖核酸(HBV-DNA)转阴率、治疗前后国际标准化比值(INR)、肝脏生化指标[总胆红素(TBIL)、总胆固醇(TC)、白蛋白(ALB)]、HBV-DNA载量及病死情况。結果 观察组患者HBV-DNA转阴率为50.00%(15/30), 高于对照组的13.33%(4/30), 差异具有统计学意义(P
简介: 【摘 要】目的:分析胃肠镜检查术应用依托咪酯复合丙泊酚静脉麻醉的效果。方法:本次研究对象为本院在 2018年 7月 -2019年 7月间接受胃肠镜检查的患者,共 90例,根据住院顺序等分成 A组和 B组, A组实施依托咪酯麻醉, B组实施依托咪酯联合丙泊酚麻醉,对 2组患者体动、肌痉挛及检查时间、清醒时间、术中依托咪酯用量进行比较。结果: B组体动、肌痉挛的发生率低于 A组 ;检查与清醒时间相比, 2组无差异( P>0.05),依托咪酯用量相比, B组明显低于 A组( P<0.05)。结论:胃肠镜检查术中运用依托咪酯复合丙泊酚静脉麻醉,有着显著安全性,可以使体动、肌痉挛等不良反应的发生率有效减少,减少依托咪酯的用量,从而确保手术的顺利开展。 【关键词】依托咪酯 ;丙泊酚 ;麻醉 ;胃肠镜检查术 ;分析 Objective: to analyze the effect of intravenous anesthesia with etomidate combined with propofol in gastroenteroscopy. Methods: 90 patients who underwent gastroenteroscopy in our hospital from July 2018 to July 2019 were divided into group A and group B according to the order of hospitalization. Group A was given etomidate anesthesia, and group B was given etomidate combined with propofol anesthesia. The body movement, muscle spasm, examination time, awake time and intraoperative etomidate dosage were compared between the two groups. Results: the incidence of body movement and muscle spasm in group B was lower than that in group A; there was no difference between the two groups in terms of examination and awake time (P > 0.05), and the dosage of etomidate in group B was significantly lower than that in group A (P < 0.05). Conclusion: the application of etomidate combined with propofol intravenous anesthesia in gastroenteroscopy has significant safety, which can effectively reduce the incidence of body movement, muscle spasm and other adverse reactions, reduce the dosage of etomidate, so as to ensure the smooth operation.
简介:【摘要】 目的 分析在纵隔肿瘤的胸腔镜治疗中,应用自主呼吸静脉麻醉与常规双腔气管插管静脉吸入复合麻醉的应用效果。方法 选取我院于 2018年 12月 ~2019年收支的纵隔良性肿瘤患者进行分析,随机分为 2组。给予对照组患者常规双腔气管插管静脉吸入复合麻醉方式下进行胸腔镜手术,切除纵隔肿瘤。观察组则应用自主呼吸静脉麻醉方式。对比两组患者的围术期指标。结果 观察组患者的围术期指标明显优于对照组患者,差异具有统计学意义( P<0.05)。结论 在纵隔肿瘤的胸腔镜治疗中应用自主呼吸静脉麻醉,能减少麻醉插管时间,促进患者的恢复,值得推广应用。