简介：Therapiesthatcomplementfreeradicalscavengingareanimportantapproachfortreatingaginginthebrain.Inthepresentstudy,twoformulationsofmoxaconemoxibustionwereappliedatacupointsZusanli(ST36)andXuanzhong(GB39),andatacupointsBaihui(DU20)andGuanyuan(RN4),inD-galactose-inducedsenilemice.TheresultsrevealedthatmoxaconemoxibustionimprovedtotalsuperoxidedismutaseandCu/Zn-superoxidedismutaseactivityinthehomogenatesofthecerebraltissue,aswellasamelioratingdeficitsinneuronalmorphologyandneuronaldensityinthecerebralcortexandhippocampalCA3.Moxaconemoxibustionalsoenhancedlearningandmemoryfunctionsofsenilemice.MoxaconemoxibustionatZusanli,Xuanzhong,BaihuiandGuanyuanacupointscanthusbeusedtocomplementfreeradicalscavengers,withefficacythatisequaltothatofelectroacupunctureatZusanliandXuanzhong,andsuperiortothatofnimodipinetreatment.