简介:一元复始,万象更新,值此新年到来之际,我谨代表世界中医药学会联合会(以下简称“世界中联),向世界中联全体会员致以诚挚的问候,向关心和支持世界中联事业发展的世界各国中医药团体致以崇高的敬意和新年的祝福!向一直关注和支持中医药事业发展的各界领导和专家、学者、同仁们表示衷心地感谢!祝大家在新的一年里生活幸福,工作顺利,平安吉祥!
简介:Over20yearsofresearchhasledtothenowwidelyacceptedroleofcardiacresynchronizationtherapy(CRT)inmedicallyrefractory,mildtoseveresystolicheartfailure(HF)withincreasedQRSduration.Inadditiontoconferringamortalitybenefit,CRThasbeenshowntoreduceHFhospitalizationratesandimprovefunctionalstatusinthispopulation.However,notallpatientsconsistentlydemonstrateapositiveresponsetoCRT.EffortstoimproveresponsetoCRThavefocusedonimprovingpatientselectionandoptimizingdeviceimplantationandfollow-up,therebycorrectingelectricalandmechanicaldyssynchrony.Inthisarticlewereviewthepathobiologyofcardiacdyssynchrony,therationalefortheuseofCRT,thehistoryandthestateoftheartofCRT,andguidelinesandrecommendationsforCRT,whilealsofocusingontheareasofcontroversyandpotentialfutureapplications.
简介:摘要目的通过分析烤瓷修复失败的原因及处理措施,总结相关经验,降低失败率。方法对19例烤瓷修复失败的患者进行失败原因分析,并进行相关补救措施,总结经验,提高修复成功率。结果结合患者的临床资料以及牙科检查发现6例牙龈变色、4例牙髓炎、3例牙龈炎、3例邻牙嵌塞、5例裂瓷。牙龈变色患者进行了局部清洗;牙龈炎患者重新调整了修复体,并且使用药消炎;牙髓炎患者进行了牙合面开髓根管治疗,其中一例拆除修复体,根管治疗后重新修复;邻牙嵌塞患者进行了拆除,最后重新进行了患牙修复;裂瓷患者进行了拆除重新修复。结论烤瓷失败主要表现为裂瓷、牙髓炎、牙龈炎、色泽变化、嵌塞等,在烤瓷牙制作过程中规范操作,保证烤瓷体的质量,提高烤瓷牙与基牙吻合性,可以提高烤瓷修复成功率。
简介:Personalizedcancermedicinehasseensignificantimprovementsoverthepastdecade.RecentElsevierconference:Miamiwintersymposium2015(MWS2015)'TowardsPersonalizedCancerMedicine'meetingwasdedicatedtothisexcitingfield,andfocusedonnewprogressinpersonalizeddrugdevelopmentandantibodydrugagainstcheckpointpathway.Thismeetingreportsummarizesthekeydevelopmentspresentedanddiscussedatthemeeting,withafocusonimmunotherapy,especiallyontheCTLA-4andPD-1/PD-L1pathways.Themonoclonalantibodydrugsinterveningthesecheckpointpathwayshavethepotentialtoplayalargerroleinpersonalizemedicinewithinthenearfuture.Hereweintendedtoprovideacomprehensivesummaryaboutongoingtrendsandfutureperspectivesonpersonalizedmedicineincancertherapy.