简介：Manypatientswithsensorineuralhearinglosshaveaprecipitoushigh-frequencylosswithrelativelygoodthresholdsinthelowfrequencies.Thispresentpaperbrieflyintroducesandcomparesthebasicprinciplesoffourtypesoffrequencyloweringalgorithmswithemphasisonnonlinearfrequencycompression(NLFC).AreviewoftheeffectsoftheNLFCalgorithmonspeechandmusicperceptionandsoundqualityappraisalisthenprovided.Forvowelperception,itseemsthatthebenefitsprovidedbyNLFCarelimited,whichareprobablyrelatedtotheparametersettingsofthecompression.Forconsonantperception,severalstudieshaveshownthatNLFCprovidesimprovedperceptionofhighfrequencyconsonantssuchas/s/and/z/.However,afewotherstudieshavedemonstratednegativeresultsinconsonantperception.Intermsofsentencerecognition,persistentuseofNLFCmightprovideimprovedperformance.Comparedtotheconventionalprocessing,NLFCdoesnotalterthespeechsoundqualityappraisalandmusicperceptionaslongasthecompressionsettingisnottooaggressive.Inthesubsequentsection,therelevantfactorswithregardtoNLFCsettings,time-courseofacclimatization,listenercharacteristics,andperceptualtasksarediscussed.AlthoughtheliteratureshowsmixedresultsontheperceptualefficacyofNLFC,thistechniqueimprovedcertainaspectsofspeechunderstandingincertainhearing-impairedlisteners.LittleresearchisavailableonspeechperceptionoutcomesinlanguagesotherthanEnglish.MoreclinicaldataareneededtoverifytheperceptualefficacyofNLFCinpatientswithprecipitoushigh-frequencyhearingloss.Suchknowledgewillhelpguideclinicalrehabilitationofthosepatients.

简介：Brief-pulsestimulationat50Hzhasbeenshowntoterminateafterdischargesobservedinepilepsypatients.However,theoptimalpulsestimulationparametersforterminatingcorticalelectricalstimulation-inducedafterdischargesremainunclear.Inthepresentstudy,weexaminedtheeffectsofdifferentbrief-pulsestimulationfrequencies(5,50and100Hz)oncorticalelectricalstimulation-inducedafterdischargesin10patientswithrefractoryepilepsy.Resultsdemonstratedthatbrief-pulsestimulationcouldterminatecorticalelectricalstimulation-inducedafterdischargesinrefractoryepilepsypatients.Inconclusion,(1)abrief-pulsestimulationwasmoreeffectivewhentheafterdischargedidnotextendtothesurroundingbrainarea.(2)Ahigherbrief-pulsestimulationfrequency(especially100Hz)wasmorelikelytoterminateanafterdischarge.(3)Alowcurrentintensityofbrief-pulsestimulationwasmorelikelytoterminateanafterdischarge.