简介：ObjectiveThemainpurposeofthepresentstudywastodescribethevestibularfunctioninpatientswithauditoryneuropathy(AN),andtoassesstheirabilitytomaintainbalance.MethodsVestibularfunctiontestswereperformedon32patientswithANand36normalsubjectsincludingelectronystagmopraphy(ENG)andstaticpostrography(SPG).Theresultsfromthetwogroupswerecompared.ResultsEquilibriumfunctioninpatientswithAN,wasabnormal,comparedtonormalsubjects.ConclusionVestibularfunctiontests,espe-ciallystaticpostrography,shouldbeperformedonpatientswithAN.

简介：BackgroundThoracoscopicminimallyinvasivepectusexcavatumrepair(Nussoperation)featuresitslittletrauma,simple,shortoperationtime,andgoodoutcomecomparedwithtraditionaltreatmentofpectusexcavatumsurgery-sternalelevation(Ravitchoperation)andsternalturnover.Theeffectoftheoperationonpatients’heartandheartfunctionremainsunclear.ThisstudyaimedtounderstandthechangesofelectrocardiogramandcardiacfunctionafterNussprocedure.MethodsFrom2008Januaryto2013July,thoracoscopicNussoperationwasperformedin217patientswithpectusexcavatum.Allthepatientsunderwentthepreoperative,postoperativedetectionofECGandcardiacfunctionin3monthsto1yearafteroperation.ResultsAfter3monthsto1yearfollow-up,arrhythmiaspersistedin46outof135patientswithpreoperativesymptoms(P<0.05);Strokevolumeandcardiacoutputsignificantlyincreased(P<0.05);Andcardiacparametersgreatlyimproved(P<0.05).ConclusionsMinimallyinvasiverepairofpectusexcavatumdeformitycancorrectthechestmalformation,alleviatearrhythmia,andimprovecardiacfunction.

简介：ObjectiveTostudytheinfluenceofJiangTangFangLongformulaoninsulinproductionandfunctioninananimalmodelofdiabetichearingloss.MethodsWistarrats(n=60)wererandomlydividedinto6groups(10ineach)toreceivenotreatment(thenormalcontrol,GroupA),ortoreceiveintra-peritoneal55mg/kgstreptozotocinwith(GroupsC,DandE)orwithout(GroupB)subsequentJiangTangFangLongformulatreatmentatvariousdosesorYuLongWantreatment(GroupF).After60days,fastingbloodglucose(FBG),bodyweight(BW)andfastinginsulin(FINS)wererecordedandtheHOMA-IRandHOMA-βcalcu-lated.Insulinexpressioninpancreatictissueswasmeasuredbyradioimmunoassay.ResultsComparedwithanimalsthatreceivedstreptozotocinwithoutrescuetreatment(GroupB),animalsthatreceivedhigherdosesofJiangTangFangLongformula(GroupsDandE)showedimprovedindicesofdiabetesmanifestation(P<0.05)andimprovedHOMA-β(P<0.05)inadose-dependentmanner,aswellasimprovedinsulinexpressioninpancreaticislets(P<0.05).ThedifferencebetweenlowdoseJiangTangFangLongformulatreatment(GroupC)andGroupBwasnotsignificant(P>0.05).ConclusionOurresultssuggestthatJiangTangFangLongformulamayimprovepancreaticβ-cellsfunctionwhichmayexplainitsefficacyintreatingdiabetichearingloss.

简介：Objective:Toexploretheeffectofearlyenteralnutrition(EN)onpostoperativenutritionalstatus,intestinalpermeability,andimmunefunctioninelderlypatientswithesophagealcancerorcardiaccancer.Methods:Atotalof96patientswithesophagealcancerorcardiaccancerwhounderwentsurgicaltreatmentinourhospitalfromJune2007toDecember2010wereenrolledinthisstudy.TheyweredividedintoENgroup(n=50)andparenteralnutrition(PN)group(n=46)basedonthenutritionsupportmodes.Thebodyweight,timetofirstflatus/defecation,averagehospitalstay,complicationsandmortalityafterthesurgeryaswellastheliverfunctionindicatorswererecordedandanalyzed.Peripheralbloodsampleswerecollectedonthedays1,4and7aftersurgery.Theplasmadiamineoxidase(DAO)activityandD-lactatelevelweredeterminedtoassesstheintestinalpermeability.TheplasmaendotoxinlevelsweredeterminedusingdynamicturbidimetricassaytoassesstheprotectiveeffectofENonintestinalmucosalbarrier.Thepostoperativebloodlevelsofinflammatorycytokinesandimmunoglobulinsweredeterminedusingenzyme-linkedimmunosorbentassay(ELISA).Results:Afterthesurgery,thetimetofirstflatus/defecation,averagehospitalstay,andcomplicationsweresignificantlylessintheENgroupthanthoseinthePNgroup(P<0.05),whereastheENgrouphadsignificantlyhigheralbuminlevelsthanthePNgroup(P<0.05).Onthe7thpostoperativeday,theDAOactivity,D-lactatelevelandendotoxincontentsweresignificantlylowerintheENgroupthanthoseinthePNgroup(allP<0.05).Inaddition,theENgrouphadsignificantlyhigherIgA,IgG,IgM,andCD4levelsthanthePNgroup(P<0.05)butsignificantlylowerIL-2,IL-6,andTNF-αlevels(P<0.05).Conclusions:Inelderlypatientswithesophagealcancerorcardiaccancer,earlyENaftersurgerycaneffectivelyimprovethenutritionalstatus,protectintestinalmucosalbarrier(byreducingplasmaendoxins),andenhancetheimmunefunction

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