简介:Retinoblastoma(RB)isthemostcommonintraocularcancerofinfancyandchildhood.ThiscancerisinitiatedbymutationonRB1,thetumorsuppressorgenethatisresponsiblefortheregulationofbothcellcycleandgnomestabilityinretinalcells.PatientswithaconstitutionalmutationonRB1canbeinherited.RBoccursapproximately1inevery15000-20000livebirths.Theworldwidemortalityforthiscancerisabout5%-11%.However,thisraterisestoabout40%-70%indevelopingcountriesduetoadelayindiagnosis.Awidevarietyofoptionsareavailableforthetreatment,butoftenacombinationoftherapiesisadoptedtooptimizeindividualizedcare.
简介:BACKGROUND:Strokepresentsasatransientorchronicbraindysfunctionandisassociatedwithhighmorbidityandhighmortality.Thedoctorsandscientistswouldliketoarguehowtoenhancethevalidityoftherehabilitationtreatmentandhowtofurtherimprovetheleveloftreatmentonstroke.OBJECTIVE:TheaimofthisstudywastoquantitativelyanalyzethecurrentworldwideprogressinresearchonstrokerehabilitationtreatmentbasedonWebofSciencedatabaseandClinicalTrial.govinthepast10years.METHODS:WeconductedaquantitativeanalysisofclinicaltrialarticlesregardingstrokerehabilitationpublishedinEnglishfrom2003to2013andindexedintheNationalInstitutesofHealthClinicalTrialsregistryandWebofSciencedatabases.DataweredownloadedonMarch15,2013.RESULTS:(1)From2003to2013,2654clinicaltrialsinvestigatingstrokewereindexedinClinicalTrials.gov.Therewereonly58clinicaltrialsregisteredin2003,andtherewasamarkedincreasefrom2005.Atotalof605clinicaltrialsontherehabilitationofstrokewereconductedinthepast10years.(2)TheanalysisshowedthatmostofthetrialsinthefieldwereregisteredbyNorthAmericaninstitutions.WithrespecttotheAsiancountries,ChinaandTaiwanareaofChinaalsopublishedareasonableproportionofthetrials,butcomparativelyspeaking,thenumberoftrialsisreallyrare.Mostoftheinterventionsweredrugs,followedbythedevices,andbehavioralinterventionswererankedthird.(3)Inthepast10years,therewere4052studiesonstrokeindexedbyWebofSciencedatabase.CONCLUSION:Fromperspectiveofresearchprogress,wefoundthatthenumberofclinicaltrialsandpapersonstrokerehabilitationhasincreasedsignificantlyinthepast10years,betweenthemaremarkablepositivecorrelationexists.
简介:目的将为服的梗塞续发症观察温暖挖出的刺破方法的临床的效果。有在有包括标准的一致的服的梗塞续发症的六十个病人随机被划分成一个治疗组和控制的方法组织,在每个组的30个盒子。控制组被给西方的药的基本治疗。治疗组被增加,针灸治疗在西方的药的治疗之上基于。在由健康的国家研究所的治疗摸规模(NIHSS)前后,病人的神经病学的缺点被估计。结果显著药品率是83.3%,全部的有效的率在治疗组是93.3%,对56.7%和70.0%处于在二个组之间的显著药品率和全部的有效的率与统计差别在控制组织(P<0.05)。在治疗以后,NIHSS分数在两个组减少了(P<0.01或P<0.05),并且差别是统计的在二个组之间重要(P<0.01)。结论温暖挖出的刺破方法比在服的梗塞续发症的治疗的西方的药的单个治疗好。
简介:观察针灸的临床的效果的目的在治疗长期的湿疹与acupoint注射治疗结合了。七十个病人随机被划分成二个组的方法。在治疗组的36个盒子在针灸方面被对待,acupoint注射治疗并且与洋梅花针拍,当在控制组的34个盒子与Halometasone的Loratadine正热门申请的口头的管理被对待时,啪啪撞击。在三星期的治疗,药品和显著的有效的率和全部的有效的率以后的结果是分别地,80.6%和97.2%在治疗组织,对47.1%和79.4%在控制组织。在在二个组之间的药品和显著的有效的率和全部的有效的率的差别是统计上重要的(所有P<0.05)。没有明显的不利反应在治疗期间出现在二个组。结论针灸正acupoint注射治疗为有安全地的高度的长期的湿疹是有效的。