学科分类
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5 个结果
  • 简介:PurposeToconfirmtheeffectsofacupuncture,andChinesemedicinesincontrollingthewithdrawalsymptomsfromtheopium-likedrugs.Method96heroin-dependentsubjectsweredividedintofourgroups,whichweretreatedrespectivelybywesternmedicine(Agroup),acupuncture(Bgroup),Chineseherbs(Cgroup),andacupuncture&Chineseherbs(Dgroup).Before,duringandaftertreatment,theconcentrationofserumtestosteroneandprolactin,andimmunefunctions(serumCD3+、CD4+、CD8+andCD4+/CD8+)weretested.ResultsAftertreatment,theconcentrationofserumtestosteroneinAandBgroupwerehigherthanbeforeandduringtreatment,andinCandDgroup,duringtreatmentwerehigher.Inthefourgroups,theconcentrationofserumprolactinbeforetreatmentwasthehighest.ThelevelsofCD3+、CD4+、CD8+andCD4+/CD8+werelowestbeforetreatmentandhighestaftertreatment.ConclusionAcupunctureandChinesemedicineseffectiveinrelievingspasmandpaincancontroltheopium-likedrugwithdrawalsymptomstodifferentdegrees,especiallyacupuncture.However,acupuncturecannoteasethewithdrawalsymptomscompletely.AcupuncturedoesnotstrikinglycooperatewiththeChinesemedicineseffectiveinrelievingspasmandpain(includingM-receptorantagonists).Indetoxification,theJiajipointsaretheprimaryonesandsymptom-basedpointsthesecondaryones.

  • 标签: Substance WITHDRAWAL Syndrome HEROIN Dependence ACUPUNCTURE
  • 简介:目的:研究针刺对海洛因依赖者脱毒末期病态心理的改善作用.方法:选用针刺疗法、阿片加针刺疗法与阿片加丁丙诺啡及阿片加韩氏戒毒仪四种脱毒方法,应用症状自评量表,研究针刺对海洛因依赖者脱毒末期90项症状清单各因子的影响.结果:针刺能改善患者的病态心理,对强迫症状、焦虑、精神病性和因子十的调节更具优势(P<0.01).结论:针刺能改善患者病态心理,有希望帮助患者平稳地进入康复期.

  • 标签: 海洛因依赖 随机对照试验 针刺疗法 中医治疗
  • 简介:1-(2-chlorophenyl)ethanol(CPE)isofhealthandenvironmentalconcernduetoitstoxicityanditsuseasaninter-mediateinpharmaceuticalmanufacturing.ThecurrentworkdealswiththecatalyticreductivedechlorinationanddetoxificationofCPEbyPd/Febimetal.CPEwaseffectivelydechlorinatedto1-phenylethanol(PE)accompaniedbytheequivalentreleaseofchloride.TheextentofCPEdechlorinationincreasedwithtemperature,FedosageandPdloading.AdecreaseinsolutionpHincreasedCPEdechlorination,resultingpresumablyfromanincreaseinhydrogenproduction.Underthespecificconditionsof20g/LPd/Fe,0.10%Pd(w/w)andinitialpH5-6,theCPEdechlorinationwascompletedwithin145min.Thedechlorinationfol-lowedapseudo-first-orderkineticswithanactivationenergyof56.7kJ/mol.TheresultsoftoxicitytestingshowedthatCPEwasverytoxictoChlorella,whereasPEshowedlittletoxicity.Thetoxicityofthereactionsolutiondeclinedgraduallyandthepro-motingeffectsonChlorellaintensifiedconsequentlywiththedechlorinationprocess.Thus,thereductivedechlorinationofCPEtoPEbyPd/Fewasadetoxificationprocess.ItmaybeusedtoeffectivelyreducethetoxicologicaleffectsofCPE-contaminatedwastewater,therebyenhancingtheperformanceofsubsequentbiologicalprocessesinwastewatertreatment.

  • 标签: 1-(2-chlorophenyl) ETHANOL (CPE) PD/FE CATALYTIC REDUCTIVE
  • 简介:Helicoverpaarmigera是在许多重要庄稼的一个关键害虫,它被化学策略主要控制。为了设法,这个害虫对杀虫药剂由于它抵抗的能力和进化正在变得挑战性。进一步,它nonhost植物上的随后的传播在最近的时间是显著的。因此,对phytochemicals和合成杀虫药剂译码抵抗机制是主要挑战。现在的工作描述消化,辩护和豁免联系了酶,这在H与chlorpyrifos抵抗被联系。armigera。H的Proteomic分析。在在用nano液体层析团spectrometry包含饮食(CH)和人工的饮食(广告)的chlorpyrifos上喂之上的armigera内脏织物鉴别在CH的upregulated23蛋白质喂了幼虫。与基因本体论分析相结合的数据库搜索表明识别内脏蛋白质在消化,为免疫关键的蛋白质,强调的适应回答,和detoxification占去。候选人蛋白质的生物化学、量的即时聚合酶链反应分析显示昆虫正在努力在CH的存在得到营养素和精力,当同时努力使chlorpyrifos产生代射变化时。而且,我们在H建议了chlorpyrifos的一条潜在的处理小径。由用煤气的层析团spectrometry检验代谢物的armigera勇气。H。到由调整蛋白质的表示的杀虫药剂的吸引人的行为的、词法改编和电阻的一个范围在消化和detoxification机制包含了处理在上面的armigera展览与chlorpyrifos。在这些上下文,作为内脏是生物信息的一个富有的仓库;内脏纸巾的深刻分析能在昆虫给detoxification和抵抗机制的线索。

  • 标签: 毒死蜱 棉铃虫 杀虫剂 毒蛋白 消化 表达调控
  • 简介:Chuanwu(CW),从AconitumcarmichaeliiDebx的母亲根的著名繁体中文药(TCM)……(Ranunculaceae),被用于各种各样的疾病的处理。不幸地,因为它的狭窄的治疗学的窗户,它的毒性经常被报导。在现在的学习,一个metabolomic方法被执行描绘phenotypically生物化学的不安和导致CW的毒性的潜在的机制。同时,在尿的毒性biomarkers的表示水平被分析与Gancao由联合评估detoxification(根值Glyeyrrhizae,CG),Baishao(根值PaeoniaeAlba,CS)并且Ganjiang(根茎Zingiberis,CJ),它从古典TCM药方被屏蔽。尿metabolomics被UPLC-Q-TOF-HDMS,和集体系列执行检测代谢物的信号系统地用模式识别方法被分析。作为结果,与CW毒性联系的十七biomarkers被识别,它与戊糖和glucuronate被联系互变现象,丙氨酸,aspartate,和glutamate新陈代谢,在其它之中。大多数毒性biomarkers的表示层次被相容性药有效地向正常范围调制。它显示三相容性药能有效地除去CW。在摘要,我们的工作证明metabolomics为TCM对毒性和发现detoxification方法的评估极其重要。

  • 标签: 药学 药剂学 调剂学 剂型