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  • 简介:AbstractIntroduction:Numerous dermatoses associated with monoclonal gammopathy have been reported in the literature. Subepidermal autoimmune bullous diseases (SABD) are one of them which were not common.Here we report a case of SABD associated with MGUS who had a severe mucosal involvement and unexpected positive direct Nikolsky phenomenon.Case presentation:A 68-year-old male patient was admitted to our clinic with erosions on the oral mucosa, tense blisters, erosions, and ulcers on the trunk and extremities. Subepidermal vesicle formation was detected in the skin biopsy. Clinical examination revealed positivity for the Nikolsky phenomenon. The disease was unresponsive to conventional treatments and dysphagia and hoarseness occurred. The patient was screened for malignancy due to his unresponsiveness to the treatments and his severe oral mucosal involvement. Ig-G MGUS was detected in the patient.Discussion:The Nikolsky sign is an indicator of acantholysis and is known as a specific finding for pemphigus. However, when we look at gammopathy-associated autoimmune bullous dermatoses, skin fragility has been reported in cases. However, the meaning of fragility is not explained. The diagnosis of all these patients was Ig-M MGUS. Our patient was presented because of non-IgM MGUS, direct Nikolsky positivity, and severe mucosal involvement.Conclusion:Nikolsky positivity may be a clue for gammopathy-related subepidermal autoimmune bullous diseases.

  • 标签: subepidermal autoimmun bullous diseases gammopathy MGUS Nikolsky phenomenon case report
  • 简介:ThispaperdescribesanewphenomenonofacousticstreamingwhichtakesplacewhenaHelmholtzresonatorisexcitedbyaninsidesoundsourcewithresonantfrequency,andtakestheformofastrongturbulentjet.Theflowvisualizations,hotwireandLDVmeasurementsarecombinedtoinvestigatetheprocessofacousticstreaming.ItisfoundthatthiskindofacousticstreamingresultsfromthecontributionofReynoldsstress.

  • 标签: ACOUSTIC STREAMING RESONANT FREQUENCY REYNOLDS STRESS
  • 简介:磨擦,一枚戒指有弹性地支持了的一个磁盘的阶段特征被调查并且过去常解释僵硬增加现象的机制。只要磨擦被维持,磁盘上的磁盘和旋转的团之间的平均阶段差别毫无疑问是不到蟺/2。当磨擦完成时,阶段差别快速来临到蟺。这行为独立于磨擦系统的物理参数。理论结果是与实验验证的品质上。关键词僵硬增加现象-阶段特征-磨擦转子这个工程被支持由在里面英国的皇家学会和中国(10672006)的国家自然科学基础的来交情。

  • 标签: 摩擦盘 刚度 机制 旋转质量 物理参数 摩擦系统
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  • 简介:Whenweareoperatinglowtemperatureplasmaindustrialgeneratororexploitinglowtemperatureplasmaapplication,wehavealwaysobservedanenhanceddischargephenomenon.Suchas,whenweareworkingonplasmanitridingtreatmenttosteelworking

  • 标签: 低温等离子体 DC发光放电 空心阴极 渗氮处理
  • 简介:Inthispaper,thephenomenononcollapsibletubedisplacementoscillation,anewbehaviorofthecollapsibletubepuisatileflowhasbeenstudied.Theexperimentsshowthatthecollapsibletube,inwhichtheflowisperiodicpuisatileintheupstream,willoscillateasasimplesupportedbeamwhenitiscollapsedtocertainextent,andthatifthetubeiscollapsedcontinue,thisoscillationwilltendtoweakandcompletelydisappearlastly.Ananalyticalmodelcorrespondingtothecollapsibletubedisplacementoscillationanditsgovernedequationsaresetupfromtheexperimentbackground.Byanalysingthemodelandsolvingtheequations,thecollapsibletubedisplacementoscillationpatternandtheoscillationoccurringordisappearingcriterionareobtained.Theresultspredictedbythisstudyareinagreementwiththoseobservedfromexperimentphenomena.

  • 标签: OSCILLATION UPSTREAM UNSTEADY governed disappear criterion
  • 简介:Tostudythemechanicalpropertiesofthefilm/substratestructure,thefiniteelementcodeABAQUSv6.9-1isadoptedtosimulatethetensilemechanicalbehaviorofthenanoscalethinfilmbondedtoasubstrate.Thebifurcationphenomenonofthestructureunderuniaxialtensionisfound:thesingle-neckdeformation,themultiple-neckdeformationandtheuniformdeformation.Thesubstrateandthefilmareregardedaspower-hardeningmaterialsobeyingtheJ2deformationtheory.Firstly,theinfluenceofmaterialhardeningmatchontensilebifurcationmodeisanalyzedunderperfectlywell-bondedinterfacecondition.Then,theeffectsofinterfacialstiffnessandothersuperficialdefectssurroundingtheimperfectiononbifurcationmodeareinvestigated.Itisconcludedthatunderthewell-bondedinterfacecondition,ifthestressofthesubstrateislargerthanthefilm,thefilmwilluniformlydeformwiththesubstrate;ifthestressofthesubstrateissmallerthanthefilm,thefilmwillformasingleneck,exceptthecasethataweakly-hardeningfilmisbondedtoasteeply-hardeningsubstratewhenmultipleneckscanbeformed.Withthedecreaseofinterfacialstiffness,theuniformdeformationmodecantransformintothemultiple-neckdeformationmode,andfurthertransformintothesingle-neckdeformationmode.Andotherdefectssurroundingtheimperfectioncaninfluencethewavelengthofdeformationandnecknumber.

  • 标签: 单轴拉伸 分叉现象 基板 电影 数值分析 均匀变形
  • 简介:Inthisstudy,thenull-fieldboundaryintegralequationmethod(BIEM)andtheimagemethodareusedtosolvetheSHwavescatteringproblemcontainingsemi-circularcanyonsandcirculartunnels.Tofullyutilizetheanalyticalpropertyofcirculargeometry,thepolarcoordinatesareusedtoexpandtheclosed-formfundamentalsolutiontothedegeneratekernel,andtheFourierseriesisalsointroducedtorepresenttheboundarydensity.Bycollocatingboundarypointstomatchboundaryconditionontheboundary,alinearalgebraicsystemisconstructed.Theunknowncoefficientsinthealgebraicsystemcanbeeasilydetermined.Inthisway,asemi-analyticalapproachisdeveloped.Followingtheexperienceofnear-trappedmodesinwaterwaveproblemsofthefullplane,thefocusingphenomenonandnear-trappedmodesfortheSHwaveproblemofthehalf-planearesolved,sincethetwoproblemsobeythesamemathematicalmodel.Inthisstudy,itisfoundthattheSHwaveproblemcontainingtwosemi-circularcanyonsandacirculartunnelhasthenear-trappedmodeandthefocusingphenomenonforaspecialincidentangleandwavenumber.Inthissituation,theamplificationfactorfortheamplitudeofdisplacementisover300.

  • 标签: 聚焦 边界条件 波浪 上海 圆形隧道 积分方程方法
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  • 简介:Fingeringphenomenaarecommonoccurrenceinthenaturalworld.Itgenerallytakesplacewhenalessviscousfluiddisplacesamoreviscousfluidtypicallyinporousmedia.Nowadays,suchphenomenahaveextensivelybeenstudiedduetoitsimportanceinmanyindustrialfields.Inthispaper,theeffectsofsurfacewettabilityonfingerpatternarestudiedandsimulatednumericallybytheLatticeBoltzmannmethod(LBM).Thedisplacementefficiencyisinvestigatedbyusingtwoparameters,namely,thebreakthroughtimeandthearealsweepefficiency.Thesimulationhasdemonstratedthatsurfacewettabilitywillinfluencethefingerpatternnomatterthegravityisconsideredornot,butinthepresenceofgravity,thefingerpatternismuchmorecomplicatedandirregularduetothecoexistenceandcompetitionofcapillaryforce,viscousforceandgravity.

  • 标签: IMMISCIBLE FLUIDS porous media VISCOUS FINGERING