简介：在第二等的自河的推迟的固体的集中经常广泛地变化，导致满足消毒标准的紫外剂量的经常的调整。Inaddition，需要的消毒率是困难的有时完成。作者学习了颗粒分布，联系粒子的烘便的大肠菌(F.C)的贡献，和他们对紫外消毒的影响。一个联合消毒过程(有随后的UVdisinfection的氯化)被测试改进消毒效果。结果显示推迟的固体的内容，特别大粒子，在紫外消毒效率上有强壮的影响；D>10个μm粒子联系了F.C。是困难的被消毒并且是在激活曲线的F.C的跟踪的主要部分。氯化前能减少在第二等的自河和变换的粒子的数字大粒子进小的，在紫外消毒上减少粒子的影响并且提高联合过程的抵抗能力到粒子装载。

简介：AbstractPathogenic bacterial infection is severely threatening public health globally. The multi-modal antibacterial nanoplatforms could significantly improve the antibacterial efficiency. Here, we report a metal(Ti)-organic framework (MOF) derived nanocarbon (C-Ti-MOF) as a biosafety material for synergistic sterilization of pathogenic bacteria via efficient photodynamic catalysis and robust photothermal effects. The C-Ti-MOF consists of abundant TiO2 nanodots embedded in graphitic carbon frameworks. Under visible light irradiation, TiO2 nanodots can catalyze H2O2 and O2 to produce superoxide anion (·O2-) and singlet oxygen (1O2), respectively. Meanwhile, under near-infrared irradiation (NIR), C-Ti-MOF can generate massive heat to destroy bacterial membranes. Systematic antibacterial experiments reveal that the C-Ti-MOF nanoagents have a long-lasting and nearly 100% bactericidal ratio at an extremely low dose (0.16 mg/mL), which is much better than the state-of-the-art TiO2 (Commercial TiO2 (P25), 0.64 mg/mL). Furthermore, the C-Ti-MOF can be electrospun into an antibacterial nanofiber membrane via mixing with polymeric matrix for treating bacteria-contaminated wastewater, and the membranes possess integrated antibacterial activity and excellent biocompatibility. Our study demonstrates a promising Ti-MOF-based biosafety material for efficient and long-life disinfection, which may stimulate new research in MOF-related biological applications in various disciplines ranging from water decontaminations to nanotherapeutics.

简介：AbstractVaporized hydrogen peroxide (VHP) is a highly active disinfectant, and VHP decontamination systems have been widely applied in hospitals, microbiological laboratories, and pharmaceutical industries. However, the decomposition of VHP into non-toxic by-products is essential. Evaluation of the disinfection efficacy of VHP is crucial to ensuring the reliability of VHP disinfection and controlling microbial contamination. In this study, a rapid and sensitive strategy is proposed to evaluate the efficacy of VHP in surface disinfection by detecting the survived and killed bacteria from VHP-exposed biological indicators (BIs). A dual-channel solid-phase cytometer is designed, and fluorescent dyes are used as indicators to automatically and accurately distinguish live cells from dead cells in the mixtures of bacteria. To verify the availability and effectiveness of the laser scanning cytometry, experiments on its application in estimating the efficacy of VHP disinfection practice have been carried out in this study, and its estimation effect compared with that of the traditional plate counting method. Results show that the proposed assay might distinctly identify live or killed cells labeled by green and red fluorescent dyes and examined the disinfection efficacy in 30 min by calculating the bactericidal rate. Compared with the plate counting method, the proposed approach is accurate and practical, with an average detection efficiency of 98.47% ± 1.55%. Moreover, an excellent correlation between the concentrations of B. subtilis var niger (ATCC 9372) measured by the proposed detection system and by the plate counting method is noticed (R2= 0.9971), indicating that this approach had advantages in the detection of trace microorganisms. To summarize, the proposed strategy appears practical and significant in many fields in which microbial counting and identification are required.