简介：BackgroundPatientswithacutetypeAaorticdissectionhaveahighincidenceofpostoperativecerebralcomplication.Betterunderstandingoftheriskfactorscouldhelptooptimizepreventionandtreatmentstrategies.MethodAtotalof298patientsofacutetypeAaorticdissectionoperatedinGuangdongCardiacInstitutionfrom2010.10to2014.12wereincluded,253ofthemweremaleandtheother45werefemale.Theiraverageagewas45.8±12.2y.Allthepatientsweredividedintocerebralcomplicationandnocerebralcomplicationgroups.Datacollectedfrombothgroupswereanalyzedbyunivariateandmultivariateanalysestoidentifytheindependentriskfactorsofpostoperativecerebralcomplication.ResultTheincidenceofpostoperativecerebralcomplicationwas37.9%(113/298).Among113patients,temporarynervedamage(TND)groupandpermanentnervedamage(PND)accountedfor93cases(31.2%)and20cases(6.7%)respectively.LogisticRegressmultivariateanalysisshowedthathistoryofhypertension(OR=2.560,95%CI,1.397-4.692,P<0.01),totalarchreplacement(OR=2.315,95%CI,1.386-3.869,P<0.01),timeofaorticarrest(OR=1.008,95%CI,1.004-1.012,P<0.01)andpostoperativehypoxemia(OR=1.858,95%CI,1.122-3.078,P<0.05)weretheindependentriskfactorsofthepostoperativecerebralcomplicationinpatientswithacutetypeAaorticdissection.ConclusionIncidenceofpostoperativecerebralcomplicationishighintheacutetypeAaorticdissectionpatientsitsmajorriskfactorsarehypertensionhistory,totalarchreplacement,andlongdurationofaorticarrestorhypoxemia.