简介：

简介：

简介：Exercise-pricepolicyisperhapsthecentraldesignissueregardingnontradableExecutiveStockOptions(ESO).Inthispaper,wegivethevaluelineofESO,V(P),andtherangeoftheincentive-maximizingexercisepriceswhichisdefinedastheexercisepricesthatgenerateincentives,εn(P)/εP,within1percentofthemaximumusingthe“certaintyequivalence”approach,similartothatadoptedbyRichardLambertetal..Ourresultsshowthat,holdingconstantthecompany'scostofmakinganoptiongrant,incentivesaremaximizedbysettingexercisepriceswithinarangethattypicallyincludesthegrant-datemarketprice.

简介：ObjectivesLittleisknownaboutthemechanismofexercise-indueedangiogenieresponseinisehemicmyoeardium.Thisstudywasdesignedtoinvestigatetheeffeetsofexercisetrainingonexpressionofvaseularendothelialgrowthfaetorandangiogenesisininfarctedheart.MethodsFiftymaleFVBmiceweredividedintothreesubgroupstotestvariousresponsestoexercise,includingtimedependentresponseofangiogenicfactorstoexercisetraininginintactheart(n=10)andinfarctedheart(n=10),aswellasexercise-inducedangiogenieresponseinheartwithmyocardialinfarction(MI)(n=30).Themiceintheexercise-traininggroupswereallowedtoexercisedailyat1hourperdayfor7days.ResultsVEGFproteinexpressionwasup-regulatedbyexercisetrainingintimedependentfashioninmicewithMI.AngiogenesiswasevidentbyincreasedmyocardialmicrovesselsobservedbyPECAM-1immunohistoc-hemicalstaininginpost-MIexercisegroup(16.5±3.4)/0.4mm^2versuspost-MIsedentarymice(10±2.1)/0.4mm^2(P<0.05).Cellproliferationassessmentshowedsignificantlyhigher(P<0.05)numberofBrdUpositivecellsinpostMImiceinexerciseerouoasopposedtosedentarypostMImice.2%TTCstainingdisclosedaprofounddifferenceinthesizeofMI(18.25±2.93)%inexercisegroupvssedentarygroup(29.26±7.64)%(P<0.05).ConclusionsActivationandup-regulationofVEGFininfarctedmiceheartmaycontributestheangiogenicresponsetoexercisetrainingattheearlystageofmyocardialinfarction.Thisunderscorestheimpactofexerciseonangiogenesisinpostmyocardialinfarctionsetting.

简介：Purpose:ToobservethetherapeuticeffectofacupuncturecombinedwithtractionandQigongexercisefortreatmentofnerve-roottypecervicalspondylosis.Methods:Atotalof130nerve-roottypecervicalspondylosispatientswererandomlydividedintoacupuncture+traction+Qigong-exercise(ATQE)group(n=59),acupuncture+Qigong-exercise(AQE)group(n=40)andtraction+Qigong-exercise(TQE)group(n=31).MainacupointsusedwereFengchi(GB20)andcervicalJiaji(EX-B2)ontheaffectedside.Results:Afteronemonth'streatment,inATQE,AQEandTQEgroups,43(72.88%),18(45.00%)and12(45.16%)hadremarkableamelioration,14(23.72%),14(35.00%)and10(32.26%)wereeffective,and2(3.39%),8(20.00%)and7(22.58%)hadnoapparentchangeswiththetotaleffectiveratesbeing96.61%,80.00%and77.41%respectively.ThetherapeuticeffectofATQEgroupwassignificantlysuperiortothatofAQEandTQEgroups(P＜0.01).