简介:AbstractBackground:Extra-corporeal video telescope operating monitor system provides a necessary instrument to perform high-precision neurosurgical procedures that could substitute or supplement the traditional surgical microscope. The present study was designed to evaluate a compact high-definition two-dimensional exoscope system for assisting in surgical removal of large vestibular schwannoma (VS), as an alternative to a binocular surgical microscope.Methods:Patients with Koos grade 3 and grade 4 VS undergoing surgery were enrolled in this prospective cohort study between January 2013 and June 2018. The demographics and tumor characteristics (size, Koos grade, composition [cystic or solid mass]) were matched between the two groups of patients. The following outcome measurements were compared between the two groups: duration of surgery, volume of blood loss, extent of tumor resection, number of operating field adjustments, pre- and post-operative facial and cochlear nerve function evaluated at 3 months post-surgery, complications and surgeons’ comfortability.Results:A total of 81 patients received tumor resection through the retrosigmoid approach under either an exoscope (cases, n = 39) or a surgical microscope (control, n = 42). Patients in the two groups had comparable tumor location (P = 0.439), Koos grading (P = 0.867), and composition (P = 0.891). While no significant differences in the duration of surgery (P = 0.172), extent of tumor resection (P = 0.858), facial function (P = 0.838), and hearing ability (P = 1.000), patients operated on under an exoscope had less blood loss (P = 0.036) and a fewer field adjustments (P < 0.001). Both primary and assistant surgeons reported a high level of comfort operating under the exoscope (P = 0.001 and P < 0.001, respectively).Conclusions:The compact high-definition two-dimensional exoscope system provides a safe and efficient means to assist in removing large VSs, as compared to a surgical microscope. After the acquaintance with a visual perception through a dynamic hint and stereoscopically viewing corresponding to the motion parallax, the exoscope system provided a comfortable, high-resolution visualization without compromising operational efficiency and patient safety.
简介:Thepresentstudywasdesignedtodevelopandvalidateasensitiveandreliableultrahighperformanceliquidchromatographycoupledwithquadrupoletime-of-flightmassspectrometry(UPLC-QTOF/MS)methodtoseparateandidentifythechemicalconstituentsofQixueShuangbuTincture(QXSBT),aclassictraditionalChinesemedicine(TCM)prescription.UndertheoptimizedUPLCandQTOF/MSconditions,56componentsinQXSBT,includingchalcones,triterpenoids,protopanaxatriol,flavonesandflavanoneswereidentifiedandtentativelycharacterizedwithinarunningtimeof42min.Thecomponentswereidentifiedbycomparingtheretentiontimes,accuratemass,andmassspectrometricfragmentationcharacteristicions,andmatchingempiricalmolecularformulawiththatofthepublishedcompounds.Inconclusion,theestablishedUPLC-QTOF/MSmethodwasreliableforarapididentificationofcomplicatedcomponentsintheTCMprescriptions.
简介:Duringthelasttwodecadesfractionalcalculushasbeenincreasinglyappliedtophysics,especiallytorheology.ItiswellknownthatthereareobiviousdifferencesbetweenRiemann-Liouville(R-L)definitionandCaputodefinition,whicharethetwomostcommonlyuseddefinitionsoffractionalderivatives.Themultipledefinitionsoffractionalderivativeshavehinderedtheapplicationoffractionalcalculusinrheology.Inthispaper,weclarifythattheR-LdefinitionandCaputodefinitionarebothTheolog...
简介:Thelongcontroversyovertheterm‘Quaternary'asachronostratigraphicunitmaybereachinganapotheosis,judgingfromrecentpapers(PillansandNaish,2004;Gibbardetal.,2005;andreferencestherein).Thedebateisnolongercenteredonwhetherthereshouldbeaplaceinthegeologicaltimescaleforaunittermed‘Quaternary'-despiteitsdubiouspast,itcannotbedeniedthatalargebodyofearth-historicalresearchisstronglyidentifiedwiththisterm.ThechallengenowconcernsanappropriaterankanddefinitionofQuaternarywithregardtootherchronostratigraphicunits.Severaloptionshavebeenproposed(PillansandNaish,2004),andGibbardetal.(2005)encourageadebateonthesebeforedecisionisreached.Inthisbriefnote,wedescribeanarrangementnotpreviouslyconsideredthatseemsadvantageous.Itisinstructive,however,tofirstreviewthePleistoceneSeriesandNeogeneSystem,thetwounitsthataredirectlyaffectedbyintroductionoftheQuaternaryintothechronostratigraphichierarchy.
简介:破坏损害被定义为avery骨头和软纸巾的严重损坏。我们在一些破裂盒子中发现了那的Butin临床的实践,软纸巾的损坏不象“destructiveinjury”一样严重显示,而弄碎破裂stillcannot表演骨头损坏的严厉。因此我们proposeda新术语“destructivefractures”在把破坏损害的定义与典型诊所盒子相结合以后。破坏破裂指谁的破裂骨状的纸巾太严重被损坏被修理,但是软纸巾,神经和静脉是严重地伤害的更少,canbe修理。从一年2001~2010,破坏破裂的75个盒子被同意进入我们的部门。根据是否与外部环境连结的破裂和破裂地点,他们被划分成6种类型:al类型,关上的骨干破坏骨折;a2类型,开的骨干破坏骨折;bl类型,关上的包含关节的破坏骨折;b2类型,开的包含关节的destructivefracture;c1类型,关上的混合破坏骨折;c2类型,开的混合破坏骨折。相应临床的治疗为破坏骨折的新分类标准是的每type.The被进行简单、实际并且thuscan被用作一个重要指南为破坏破裂做合理treatmentplans。
简介:Likevaluechainandsupplychain,“industrialchain”becomesthefocusofattention.Theimplicationof“industrialchain”hasgainedalargerangeofextension.Itnotonlyexpressestheindustrial“chain”structureandrelationshipof“backandforward”inorderor“upanddown”indirection,butalsoitrepresentsaclusteroflargescaleoffirmsinanareaorcolony.Itisanetwork,oracommunity.Consequently,weconcludethat“industrialchain”isasynthesisofindustrialchain,industrialcluster,orindustrialnetwork.Inthisarticle,firstlywewilldistinguishindustrychainfromindustry.Anindustryisthecollectionoffirmsthathavethesameattribute,soanindustrycanbedefinedbyfirmcollectionofcertainattribute.Weindicatethatindustrialchainisakindofverticalandorderlyindustriallink.Itisdefinedaccordingtoaseriesofspecificproductorservicecreated.Secondlyweanalyzetheverticalorderlydefiinitionprocessfromtheaspectsofsocialdivisionoflaborandrequirementdivision,self-organizationsystem,andvalueanalysis.Non-symmetryanddependingonsystemorcommunityoflargescaleofindustrialunitsleadtoentireindustryto“orderly”structure.Ontheotherhand,thedraughtofdiversityandcomplexityofrequirementsimultaneouslyleadtoentireindustrytobemore“orderly”.Alongwithprocessesofself-organization,industrialwillappi'oachthestateofmoreorderlyandsteady,andconstantlymakeindustrialchainupgrade.Eachfirmorunit,whowillgainthevalue,hastoestablishchannelsofvalue,whichwecalled“industrialvaluechain”.Lastly,wediscusstheconsequenceofverticalandorderlydefinition,whichisexhibitedbyacertainrelationshipbody.Thetypicalformsofindustrialchainincludeindustrialcluster,strategyallianceandverticalintegrationetc.
简介:InEgyptologydealingwithbothhistoricalandliterarytextsoftenraisesthequestionoftheirpoliticalintention.Thealmostfixedplotofthe"Knigsnovelle”andthe“annals,"typicalformsofrecordingEgyptianhistory,seemstoreflecttherigidEgyptianviewofhistoryanchoredinideology.Thehistoricalcourseofevents,whatwemaycall“reality,”islesssignificantthanthecoursepostulated