简介：多学科综合治疗协作组（MDT）诊治模式符合精准医学和个体化治疗的准则,目前已经发展成为消化肿瘤诊治的一种主流模式。现代消化道肿瘤的诊治需要外科、肿瘤内科、放疗科、化疗科、病理科、影像科等多学科专业团队的紧密合作。

简介：多学科综合治疗协作组（MDT）诊治模式符合精准医学和个体化治疗的准则,目前已经发展成为消化肿瘤诊治的一种主流模式.现代消化道肿瘤的诊治需要外科、肿瘤内科、放疗科、化疗科、病理科、影像科等多学科专业团队的紧密合作.为此,我刊特意开辟了“MDT病例讨论”栏目,旨在倡导和推广这一临床诊疗模式,提髙消化肿瘤的诊治水平,真正实现精准化和个体化医疗.本刊中MDT讨论文章等同论著发表,现向开展MDT诊疗的单位广泛征稿,欢迎大家踊跃投稿.

简介：摘要直肠癌是我国常见的恶性肿瘤之一，传统的手术和术后化疗的临床治疗模式疗效并不理想。多学科综合治疗是直肠癌最佳治疗的模式，准确的直肠癌治疗前评估是直肠癌综合治疗方案实施的需要，个体化原则基础上进行的术前新辅助放化疗、术中规范化手术、术中腹腔内温热化疗和术后辅助放化疗等多学科合作的综合治疗，可明显改善了直肠癌的疗效。本文对此复习相关文献，对国内外直肠癌综合治疗进行综述。

简介：摘要：外泌体类产品是基于干细胞理念的细胞学抗衰，它是通过细胞因子和活性物质去刺激细胞的活化最终达到抗衰的效果。这种作用于皮肤衰老底层逻辑的抗衰诊疗方式，虽起效时间有一定的滞后性，但是抗衰效果的持续性特别长，它和Ⅲ型胶原蛋白以及光电仪器类联合抗衰，可以起到治标又治本的作用，它们是可以作为相互互补的存在。

简介：AbstractInterleukins (ILs) and associated cytokines serve as the means of communication for immune cells and non-immune cells. The use of ILs in harnessing the immune system to cancer treatment has been a promising approach. ILs not only nurture an environment enabling cancer growth but also simultaneously trigger a productive tumor-directed immune response. These properties of ILs are increasingly being explored as a strategy to improve the outcomes of cancer. Here, we describe recently innovative technological approaches that have been developed to improve the pharmacokinetics, safety, and efficacies of IL-2, 15, 10, and 18 in the treatment of melanoma. Furthermore, the combination of ILs and immune checkpoint inhibition may synergize to reshape the tumor environment, thus yielding better clinical benefits in the future.

简介：摘要院本文介绍了60MDT地面钻机的几种钻进方式，指出了各种钻进方式的不同应用场合和各自的特点，对潜孔锤进行了重点介绍，对潜孔锤的钻进速度，回转速度，下压力，转矩等分别进行了阐述。

简介：摘要：MDT模式通过跨学科合作，汇集不同专业人员的知识和技能，以更全面、细致地处理复杂病例。尽管其优势明显，MDT模式在实际应用中仍面临诸多挑战，如沟通效率、决策一致性以及资源配置等问题。研究旨在探究如何在MDT模式下有效管理病例内涵质量，确保患者获得最优质的医疗服务，同时提高医疗团队的工作效率和满意度。

简介：应用针剌结合耳穴贴压方法治疗老年人呃逆。针剌的主穴是内关，足三里和天突。年老体虚病重者加气海和太溪，脑血管疾病者加攒竹，消化道疾病及便秘者加支沟，呼吸道疾病者加合谷。同时贴压耳穴膈，胃。耳神门，交感，皮质下和肾。结果痊愈45例，好转10例．有效率100％。

简介：AbstractTuberculosis (TB) is among the deadliest infectious diseases worldwide. Although the existing antituberculosis (anti-TB) drugs remain to be effective, the administration of these complex anti-TB drug combinations with obvious toxicity often leads to patients’ nonadherence. This may contribute toward the emergence of drug-resistant strains as well as lead to treatment failure and relapse. Therefore, in the past half century, the main focus of anti-TB drug research was to reduce the frequency of administration and toxicity and improve patients' compliance and drug sensitivity. Following these principles, the development of engineered biosafety materials is one of the most effective and promising methods in resolving these challenges. Compared with traditional drugs, biosafety materials provide a viable platform for treating TB, which are beneficial in reducing the frequency of drug administration and systemic toxicity, improving patients’ compliance and drug sensitivity, and enhancing drug targeting. In this review, we summarized the application of biosafety materials in treatment of TB in recent years and discussed the challenges faced when developing a safe, more effective, and economical pharmacotherapy against TB.

简介：Primaryesophagealadenocarcinoma(PEAC)isararemalignantdiseaseofesophagus.Becauseofitslowerincidence,theknowledgeaboutitislimitedandtherearesomeproblemsrequiringfurtherstudy.Duringrecent30years,106patientswithPEAChadbeentfeatedsurgicallyinourdepartment...

简介：Theuseoflaparoscopyhasbeenestablishedinimprovingperioperativeandpostoperativeoutcomesforpatientswithsimpleappendicitis.Laparoscopicappendectomyisassociatedwithlesswoundpain,lesswoundinfection,ashorterhospitalstay,andfasteroverallrecoverywhencomparedtotheopenappendectomyforuncomplicatedcases.Inthepasttwodecades,theuseoflaparoscopyforthetreatmentofperforatedappendicitistotaketheadvantagesofminimallyinvasivenesshasincreased.Thisarticlereviewedtheprevalence,approaches,safetydisclaimers,perioperativeandpostoperativeoutcomesofthelaparoscopicappendectomyinthetreatmentofpatientswithperforatedappendicitis.Specialissuesincludingtheconversion,intervalappendectomy,laparoscopicapproachforelderlyorobesepatientarealsodiscussedtodefinetheroleoflaparoscopictreatmentforpatientswithperforatedappendicitis.

简介：<正>OtitisMediaisacommondiseaseinthepracticeofotolaryngologyandoneofthefamous"threeinflammationsandonedeafness".Otitismediahasbeenwithhumansfromtheverybeginning.Treatmentforotitismediastartedinthewestin1774andmuchlaterinChina.

简介：Althoughmanytraditionaltherapiesareavailableforgenitalwarts(GW)，oneofthemajorproblemsinthetreatmentofGWisahighrecurrenencerate．Inordertoresolvetheproblemofrecurrence，newtheraputicapproacheshavebeeninvestigated．Newapproachesbeingexploredinclude5-fluorouracil／epinephrineinjectablecollagengel,5％imiguimodcreamandhumanpapillomavirusvaccine．Fluorouracil／epinephrineinjectablecollagengelachieveshighconcentrationoffluorouracilatthesiteofinjection．Imiguimodisanovelimmune-responesmodifier,givinggoodclearanceratesandtolerablesideeffects．AlthoughtheuseofanHPVvaccineisfaraway，preliminarystudiesshowthatitmaybepossibletodevelopsuitableprophylacticandtherapeuticvaccinestogenitalwarts．

简介：无

简介：瞄准：与高潮的机能障碍在人的治疗学习育亨宾硷的效果。方法：育亨宾硷的A20-mg剂量首先在诊所与不同原因论的高潮的机能障碍被给29个人。病人们然后被允许在更赞成的情形下面在家(滴定)增加剂量。结果和副作用随后被估计。结果：病人被分类进三组高潮的机能障碍：主要完全(13)，主要不完全(8)并且第二等(8)。梦遗在75%,40%是在场的，在上面的50%病人组织，分别地(总的来说平均62%)。因为富饶问题(52%)，介绍的人或因为他们想要经历高潮(48%)的快乐。完成了治疗的29个病人，16设法到达高潮并且也在手淫或性交期间是有能力的脚趾投掷。进一步，三完成了的A达到高潮，但是仅仅与一个震荡器的另外的刺激。前面的梦遗的历史在高潮在被劝诱的69%人是在场的但是仅仅50%没有通过治疗。病人，二随后生了孩子(双胞胎的一个集合)，3个人也是的另外一个治好。副作用不是足够的引起这些人停止治疗。结论：Yohimbineis在高潮的机能障碍的一种有用治疗选择。

简介：56patientswithtinnitusweretreatedforthreeweeksintheInselkinikHefingsdorfincompetencecenteroftinnituswithacupuncture,modempsychosomatictherapy,alliedwithhyperbaricoxygentherapy.TheTCMinterventionconsistedofmedicalacupuncturetwiceaweekand“Fivedementspalm”Qi-gongtrainingthreetimesperweek.SpecificconstellationofacupuncturepointswerechosenaccordingtotheprescriptionoftraditionalChinesestandardsandmodifiedtowelltestedpreprovedacupuncturestudy.

简介：

简介：摘要胰腺癌新辅助治疗作为胰腺癌治疗的新方向，已被证实可改善患者预后。新辅助治疗在多学科诊治(MDT)模式下，集合多学科优势，解决患者在诊断和治疗中的难题，提供精准全面且个体化的诊疗措施，使患者临床受益最大化。本文总结现阶段胰腺癌新辅助治疗在患者选择、治疗方案选择、疗效评价和手术选择中仍存在的问题，探索MDT模式下开展临床研究和胰腺癌新辅助治疗的方向。

简介：摘要：MDT在网络优化过程中，获取的相关参数主要是通过手机上报的MR测量报告，从而辅助网络精准评估、优化及规划。MDT的优点在于缩短了优化周期，减少了路测开销，有效降低了运营商的网络优化和维护成本。MDT可以精确定位，定位精度10～20米。另外MDT还可以采集全区域用户测量信息，可以更客观的评估网络性能，评估结果更加贴近用户体验。

简介：AbstractBackground:Early treatment for patients with aneurysmal subarachnoid hemorrhage (aSAH) could significantly reduce the risk of re-bleeding and improve clinical outcomes. We assessed the different time intervals from the initial hemorrhage, admission, and endovascular treatment and identified the risk factors contributing to delay.Methods:Between February 2017 and December 2019, 422 consecutive aSAH patients treated in a high-volume hospital were collected and reviewed. Risk factors contributing to admission delay and treatment delay were analyzed with univariate and multivariate analysis.Results:One hundred twenty-two (28.9%) were admitted to the high-volume hospital at the day of symptom onset and 386 (91.5%) were treated with endovascular management at the same day of admission. The multivariate analysis found that younger age (P = 0.022, OR = 0.981, 95% CI 0.964-0.997) and good Fisher score (P = 0.002, OR = 0.420, 95% CI 0.245-0.721) were independent risk factors of admission delay. None was found to be related with treatment delay. Multivariate analysis (OR (95% CI)) showed that higher age 1.027 (1.004-1.050), poorer Fisher score 3.496 (1.993-6.135), larger aneurysmal size 1.112 (1.017-1.216), and shorter interval between onset to admission 1.845 (1.018-3.344) were independent risk factors of poorer clinical outcome.Conclusion:Treatment delay was mainly caused by pre-hospital delay including delayed admission and delayed transfer. Our experience showed that cerebrovascular team could provide early treatment for aSAH patients. Younger age and good Fisher score were significantly related with admission delay. However, admission delay was further significantly correlated with better clinical outcome.