简介：Migraine,amoderatetoseverechronicheadacheoccurringononeorbothsides,isacommondiseaseaffectsyoungpeople.Althoughhearinglossinsubjectswithmigraineisnotrare,thecorrelationofmigrainewithhearinglossisnotclear.Inthisstudy,weexaminedhearinglossinyoungmigrainesubjectstodetermineifmigrainemaybeafactorincausingcochleardysfunction.Sevencollegestudentswithmigraineandthreeagematchedsubjectswithouthistoryofmigrainewereassessedusingextendedhighfrequencyaudiometryanddistortionproductotoacousticemissions(DPOAEs).Therewasnosignificantdifferenceinregularaudiomeirythresholdbetweenthemigrainegroupandthecontrolgroup.However,highfrequencyaudiometry(9-16kHz)showedthresholdsat25dBnHLorhigherinsixoutoftwentyearsinthemigrainegroup.TheamplitudeofDPOAEswerereducedformorethan10dBinthemigrainegroupincomparisonwiththecontrolgroup.ThesedatasuggestthatmigrainemayaffectcochleardysfunctionevidencedbythereducedamplitudeofDPOAEandhighfrequencypure-toneaudiometry.

简介：Objectives:Theaimofourstudyistoexaminevestibular-evokedmyogenicpotentials(VEMPs)elicitedbythegalvanicvestibularstimulationinthesternocleidomastoidmuscle(SCM)inhealthysubjectsforclinicalapplicationsofauditoryneuropathyorvestibularneuropathyinthefuture.Methods:WeenrolledsixteenhealthysubjectstorecordtheaverageresponsesofSCMtogalvanicvestibularstimulation(GVS)[current3mA;duration1ms]byelectromyography(EMG).SPSS18.0softwarewasusedtoanalyzetheobtaineddataformeanandstandarddeviation.Results:Inallhealthysubjectsmastoid-foreheadgalvanicvestibularstimulationproducedapositive-negativebiphasicEMGresponsesonSCMipsilateraltothecathodalelectrode.Thelatencyofp13was11.7±3.0ms.Thelatencyofn23was17.8±3.4ms.Theamplitudeofp13-n23was147.0±69.0mV.Theinterauralasymmetryratio(AR)ofp13,n23latencyandtheamplitudewasrespectively0.12±0.09,0.08±0.08and0.16±0.10.Discussions:GalvanicvestibularstimulationcouldelicitbiphasicEMGresponsesfromSCMviathevestibularnervebutnotfromtheotolithorgans.Galvanicstimulationtogetherwithairconductedsound(ACS)orboneconductedvibration(BCV)canelicitVEMPsandmayenablethedifferentiationofretrolabyrinthinelesionsfromlabyrinthinelesionsinvestibularsystem.