简介:The9thInternationalCongressonPeritonealSurfaceMalignancies,sponsoredbythePeritonealSurfaceOncologyGroupInternational(PSOGI)andorganizedbytheNetherlandsCancerInstitute,washeldinAmsterdam,theNetherlands,fromOctober9to11,2014,withover650delegatesfrom66countriesattendingthemeeting.Withthecentralthemetosummarizetheglobalprogressesinperitonealcarcinomatosis(PC)diagnosisandtreatment,todrafttheoutlineframeworkofinternational
简介:Objective:IL-22-producingCD4+Thelpercells(Th22cells)havebeenidentifiedasmajorinducersoftissueinflammationandimmuneresponses.Currently,nopreviousstudyexploredtheroleofTh22cellsinthepathogenesisofhepatocellularcarcinoma(HCC).ThestudyaimedtodeterminethebiologicalfunctionofTh22cellsanditseffectorIL-22inHCCpatients.Methods:Forty-fiveHCCpatientsand19healthycontrolswererecruitedandtheirperipheralbloodwascollected.ThefreshHCCtissues,adjacentHCCtissuesandtennormallivertissueswerealsocollected.FlowcytometryanalysiswasusedtodeterminethefrequenciesofcirculatingTh22cellsandTh17cells.SerumIL-22levelsweretestedbyenzyme-linkedimmunosorbentassay(ELISA).Immunohistochemicalstainingandreal-timepolymerasechainreaction(PCR)wereusedtodetectIL-22proteinandmRNAintissuesspecimens,respectively.Results:CirculatingTh22cells,Th17cellsandserumIL-22levelsweresignificantlyelevatedinHCCpatientscomparedwiththoseofhealthycontrols(P<0.001).Th22cellswereshowedtobepositivelycorrelatedwithIL-22inHCCpatients(P<0.05),butnotinhealthycontrols.NosignificantdifferenceswerefoundinHCCpatientswithHBeAgpositivityornegativityintermofTh22cellsandserumIL-22levels.TheexpressionofIL-22proteinandmRNAwashighestinHCCtissues,followedbyadjacentHCCtissuesandnormallivertissues.Furthermore,Th22cells,serumIL-22levelsandIL-22mRNAwereelevatedatstageIII-IVcomparedwithstageI-IIofHCC(P<0.05).Conclusions:ElevationofcirculatingTh22cellsandIL-22maybeimplicatedinthepathogenesisofHCC,andpotentiallybecellulartargetsfortherapeuticintervention.
简介:MyChinesefriendsoftentalkaboutthe“2000-yearfriendshipand50-yearantagonism”.Iunderstandthatitisreferredtothe2000-yearhistoryoffriendlyexchangeswithfocusonculturesbetweenJapanandChina,andtothe50-yearJapanesewarsofinvadingChina,fromtheJapan-Qingwarin1894tothedefeatofJapanin1945.However,manyChinesefriendsdonotliketoterWWII.mentionthe60yearsafterWWII.
简介:Dearcolleaguesanddistinguishedguests:Onbehalfoftheorganizingcommitteeofthe11thSouthChinaInternationalCongressofCardiology(SCC),itisourdistincthonortoinviteyoutoattendtheSCCCongress,whichisgoingtobeheldon9-12April,2009atDongfangHotel,Guangzhou,China.
简介:<正>August27-29,asamemberoftheChineseNGODelegation,Itookpartinthe65thAnnualUNDPI/NGOConferenceheldinUNheadquartersinNewYork.Thethemeofthisconferencewas"2015andBeyond:OurActionAgenda".2015willbethefinalyearofUNMillenniumDevelopmentGoal(MDG)andwitnessthe70anniversaryofUN.This
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简介: OnApril23,2006,theOpeningCeremonyof"FotonCup"theFourthChinaInternational(Syria)AutoExhibitionTour(CIAET)washeldinDamascus.SyrianMinisterofEconomyandTrade,DirectorofSyrianChamberofCommerce,IraqiAmbassadortoSyria,ChineseAmbassadortoSyria,CounselloroftheEconomicandCommercialCounsellor'sOfficeoftheEmbassyofP.R.ChinainSyriaattendedtheceremony.……
简介:摘要目的探讨2型固有淋巴细胞(ILC2)与结核分枝杆菌(Mycobacterium tuberculosis,Mtb)不同感染者外周血中Treg/Th17比值的相关性研究。方法选取初治肺结核患者(ATB组)30例和复治肺结核患者(RTB组)26例,潜伏Mtb感染者(LTBI组)22例,结核菌素皮肤试验阴性者(TST-组)17例。采用流式细胞术检测各组外周血中ILC2占CD45+细胞比例、Th17和Treg细胞分别占CD4+T淋巴细胞比例,实时荧光定量PCR法检测Foxp3 mRNA、RORγt mRNA,Pearson法进行ATB组和RTB组患者外周血中Th17与Treg相关性、ILC2与Treg/Th17比值相关性分析。结果RTB组和ATB组ILC2比例明显高于LTBI组和TST-组,且RTB组中的ILC2比例明显高于ATB组(P<0.05)。RTB组中的Th17比例低于ATB组(P<0.05),且两组均低于LTBI组和TST-组。RTB组中的Treg比例低于ATB组(P<0.05),且接近于LTBI组和TST-组,但ATB组和RTB组中的Treg/Th17比值均高于LTBI组和TST-组,两组间差异无统计学意义(P>0.05),Foxp3 mRNA、RORγt mRNA和Foxp3/RORγt比随之发生一样的变化。同时,发现在ATB组和RTB组中Th17与Treg均无相关性(r=0.023, P=0.444; r=0.428, P=0.150)。ATB组ILC2与Treg/Th17比值之间成正相关(r=0.794, P=0.000),RTB组ILC2与Treg/Th17比值之间未发现有相关性(r=0.197, P=0.297)。结论本研究肺结核患者外周血中ILC2增高,且RTB组高于ATB组;RTB组中Th17在外周血中所占比例低,并参与炎症反应,而RTB组中的Treg未参与炎症反应,但在ATB组中可能有一定的抑制作用,进一步研究发现Th17参与的炎症反应未受到Treg的调控。ILC2参与ATB患者Treg/Th17失衡,而在RTB患者中未发现此现象。
简介:摘要目的探究给予慢性阻塞性肺疾病(COPD)稳定期患者金水宝胶囊辅助治疗,对其辅助性T细胞17(Th17细胞)、Th17细胞/调节性T细胞(Treg细胞)的影响。方法选取2017年4月至2019年8月接受治疗的72例COPD稳定期患者,行随机数表法分为对照组(36例,常规治疗)和观察组(36例,常规治疗+金水宝胶囊辅助治疗),比较两组患者临床疗效、Th17细胞、Th17细胞/Treg细胞水平及不良反应。结果观察组患者治疗总有效率为88.89%(32/36),高于对照组的69.44%(25/36),差异有统计学意义(χ2 =4.126,P=0.042);治疗后,观察组Th17细胞值高于对照组[(1.52±0.52)%比(1.25±0.47)%],Th17细胞/Treg细胞值高于对照组[(0.58±0.13)比(0.49±0.15)],差异均有统计学意义(t=2.311、2.721,P=0.024、0.008);观察组不良反应发生率为2.78%(1/36),对照组不良反应发生率为8.33%(3/36),组间比较差异无统计学意义(χ2 =0.265,P=0.304)。结论金水宝胶囊辅助治疗可提升COPD稳定期临床疗效,提高Th17细胞、Th17细胞/Treg细胞值,同时控制不良反应发生。
简介:The10thCoalGeologyConference,jointlyorganizedbytheFacultyofScienceoftheCharlesUniversityinPrague,theCzechGeologicalSurveyandtheInstituteofGeologyoftheAcademyofSciencesoftheCzechRepublic,tookplaceinJune7-11,2004,attheFacultyofScience.Thecoalgeologyconferenceshavebeenheldatthefacultyeverythreeorfouryearssince1972.Theywereprecededbycoalgeologyseminarswhichbeganevenearlier,inJanuary1968.Theseseminarsandconferencesprovidedanexcellentopportunitytoexchangeknowledgeandnewinformationoncoalgeologyandrelatedfieldsand,aboveall,tobringtogetherpeoplefromvariousfieldsstartingwithscienceandendingupwithawidespectrumofinterests.
简介:18thExecutiveCommitteeMeetingofPartnersinPopulationandDevelopmentwasheldon23-24June,2011inDalian,China.LiBin,MinisterofNationalPopulationandFamilyPlanningCommission(NPFPC)ofChinapresentedherselfastheViceChairofPPDanddeliveredaspeech.Therewereabout30peopleattendingthemeeting,includingDr.Azad,MinisterofHealthandFamilyWelfareofIndia,Prof.Dr.RuhalHaque,MinisterofHealthandFamilyWelfareofBangladesh,ZhaoBaige,ViceMinisterof
简介:2011(11th)ChinaSymposiumonMonolithicRefractorieswassuc-cessfullyheldinShanghaionSept.24-26,2011.ThesymposiumwassponsoredbyRefractoriesBranchofTheChineseSocietyforMetals,
简介:RareearthmarketwasinactiveaffectedbysluggishdemandfordidymiummischmetalanddysprosiummetalbyNdFeBindustry.Mostenterpriseswerewaitingtoseewhatwasgoingonwiththeindustry.However,priceofdidymiumoxideroseagainandpriceofheavyrareearthskeptstrong.PriceofDyoxideandYtoxidekeptonrising.
简介:BaotouResearchInstituteofRareEarths(BRIREhereinafter)wasestablishedin1963.ItisthelargestcomprehensivescientificresearchandtechnologicaldevelopmentinstitutiononrareearthsinChina,coveringthefieldsofrareearthmetallurgy,environmentalprotection,newrareearthperformancematerials,rareearthapplicationinhightechfields,rareearthassayandrareearth