简介:随着现代生物科技的迅猛发展,一种新型的医学方法——基因治疗,已取得了令人瞩目的成就,人体基因治疗的成功给某些长期深受疾病困扰的患者带来了根治的希望。然而,可悲的是,一些专业人士试图把基因疗法用于运动员身体素质的改造,借此提高运动成绩。基因兴奋剂使用一旦成功,其高效件、隐蔽性必将使心怀叵测者趋之若鹜,甚至不惜铤而走险。根据目前的科技发展水平,专业人员已可以按照需要对运动员的基因产生的蛋白质与人体天然形成的蛋白质几乎完全相同。与其他兴奋剂相比,基因兴奋剂的隐蔽性更强,对人体的潜存危害性还鲜为人知,目前尚无切实有效的检测方法与手段。需要引起注意的有以下几种基引兴奋剂:
简介:Background:Accelerometershavebeensuggestedtoprovideadditionalinformationduringthe6-minwalktestwhichmaybeusefulinevaluatingchangesinfunctionalexercisecapacity.TheaimofthestudywastoidentifywhethertheadditionalinformationmeasuredbytheMyWellnessKey~(TM)(MWK)accelerometerduringatreadmill6-minwalktest(t-6MWT)wasrelatedtocurrentlyusedoutcomemeasures.Methods:Fifteenparticipants(9males,6females)performedaself-pacedt-6MWT.RespiratorygasanalysisandwalkingdistanceweremeasuredwhilstwearingtheMWK.Results:Asignificantcorrelationwasestablishedbetweenactivitycountsand6-minwalkdistance(6MWD)(r=-0.847,p<0.001)yetnot6-minwalkwork(6MWW)(r=-0.337,p=0.220).EnergyexpenditureestimatedbytheMWKwasstronglycorrelatedto6MWW(r=0.938,p<0.001)butnot6MWD(r=0.477,p=0.072).TheMWKsignificantlyunderestimatedenergyexpenditure(36.73,CI=33.9-39.7kcal)comparedtogasanalysis(54.35,CI=46.2-61.4kcal)demonstratingpooragreementbetweenthetwoanalyses(Bias=-17.61kcal,Limitsofagreement=-37.4,t2.2kcal).Measurementoftimespentundertakinglight,moderate,andvigorousphysicalactivitywasnotsignificantlydifferent(p>0.05)betweentheMWKandgasanalysis.Conclusion:EstimatedenergyexpenditureprovidedbytheMWKwasstronglycorrelatedto6MWW;however,MWKunderestimatedenergyexpenditureasmeasuredbygasanalysis.TheMWKmayprovideoutcomedatathatsupplementthosecurrentlyprovidedbythe6MWDforfunctionalcapacityassessmentduringthet-6MWT.