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  • 简介:【摘要】目的: 分析探讨外周血 MPV,PDW 与血清 CEA 联合检测对胃癌和胃溃疡的鉴别诊断的临床价值。 方法: 选取我院 2019.4-2020.4 内收治的 25 名胃癌患者( A 组)和 25 名胃溃疡患者( B 组 )以及 25 名正常患者( C 组) ,比较三组患者的外周血 MPV,PDW 指标和血清 CEA 水平。 结果: A,B 两组的 PDW , CEA 水平高于 C 组, MPV 低于 C 组,差异有统计学意义( P < 0.05 )。 A 组的 PDW , CEA 水平高于 B 组, MPV 低于 B 组,差异有统计学意义( P < 0.05 )。 结论 : 胃癌与胃溃疡患者的 MPV,PDW , CEA 水平存在差异,外周血 MPV,PDW 与血清 CEA 联合检测对胃癌和胃溃疡的鉴别诊断具有参考价值。

  • 标签: 血清 CEA MPV PDW 鉴别 胃癌 胃溃疡
  • 简介:  【摘要】 目的 进一步研究干扰素体外释放联免疫检验技术在结核病诊断中的优势, 为未来进一步提高结核病检出率奠定基础。方法 138 例患者, 分别接受结核菌素皮肤过敏试验与干扰素体外释放联免疫检验。比较两种检查方法诊断结核病的灵敏度、特异度 ; 不同结核病患者干扰素体外释放联免疫检验诊断准确率。结果 138 例患者, 病理确诊结核病 42 例, 非结核病 96 例。干扰素体外释放联免疫检验诊断结核病的灵敏度为 85.71% ( 36/42 )、特异度为 90.63% ( 87/96 ), 均高于结核菌素皮肤过敏试验的 66.67% ( 28/42 )、 80.21% ( 77/96 ), 差异具有统计学意义( P<0.05 )。肺结核患者 27 例, 肺外结核患者 15 例。肺外结核患者干扰素体外释放联免疫检验诊断准确率为 100.00% , 高于肺结核患者的 77.78% , 差异具有统计学意义( P<0.05 )。结论 干扰素体外释放联免疫检验方法满足结核病临床诊断的需求, 该诊断方法具有更高的阳性检出率, 并且还具有操作步骤简单、结果精准等优点, 能够减少误诊、漏诊等情况发生, 为结核病的早期预防、早期治疗奠定基础, 因此值得在临床上做进一步推广。   【关键词】 干扰素体外释放联免疫检验技术 ; 结核病 ; 结核菌素皮肤过敏试验 [Abstract] objective to further study the advantages of in vitro release of interferon enzyme-linked immunosorbent assay (ELISA) in the diagnosis of tuberculosis and lay a foundation for further improving the detection rate of tuberculosis in the future. Methods 138 patients were tested by tuberculin skin allergy test and interferon releasing enzyme-linked immunosorbent assay. The sensitivity and specificity of the two methods were compared, and the diagnostic accuracy of ELISA for ifn-ifn-release in vitro in different tuberculosis patients was compared. Results of the 138 patients, 42 were confirmed by pathology and 96 were non tuberculosis. The sensitivity and specificity of ELISA were 85.71% (36 / 42) and 90.63% (87 / 96) respectively, which were higher than 66.67% (28 / 42) and 80.21% (77 / 96) of tuberculin skin allergy test. There were 27 cases of tuberculosis and 15 cases of extrapulmonary tuberculosis. The diagnostic accuracy of ELISA was 100.00%, higher than that of 77.78% (P < 0.05). Conclusion the ELISA method of interferon releasing in vitro can meet the needs of clinical diagnosis of tuberculosis. This method has higher positive detection rate, simple operation steps and accurate results, which can reduce misdiagnosis and missed diagnosis and lay a foundation for early prevention and treatment of tuberculosis, Therefore, it is worthy of further promotion in clinical practice.

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  • 简介:  【摘要】 目的 观察瑞替普溶栓治疗急性ST段抬高型心肌梗死患者的疗效及安全性。方法 将68例急性ST段抬高型心肌梗死患者随机分为两组,瑞替普组34例,以瑞替普20 mu间隔30 min,分2次静脉推注溶栓;尿激酶组34例,以尿激酶150U,30 min静脉滴注溶栓。比较两组的再通率、出血并发症的发生率及过敏反应。结果 瑞替普组的梗死相关动脉总开通率明显高于尿激酶组,有明显差异(PO.05)。结论 瑞替普是治疗急性心肌梗死安全有效的溶栓药物。 

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