简介：Ltmedisease(Lymeborreliosis)iscausedbythetick-bornespiro-elraeteBorreliaburgdooCeri.Erythemamigrans,anearlyskinlesion,isthemostcommonclinicalpresentation.Theorganismmayspread,causingvariouslatermanifestations.

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简介：Asthmadevelopsinaboutoneadultperthousandpopulationperyear,andepidemiologicalstudiesindicatethatabout10%ofcasescanbeattributedtoexposuresatwork.However,occupationalasthmaisidentifiedlesscommonlythanthisinclinicalpractice;anincidenceof800-1000casesperyearisestimatedbytheUKSurveillanceofWork-RelatedandOccupationalRespiratoryDiseasescheme.Occupationalasthmaiseasilymissedbecause,apartfromitsassociationwithwork,

简介：Paget'sdiseaseofboneisafocaldisorderofboneremodellingcausedbyabnormallyincreasedosteoclast-mediatedboneresorption.qtleaffectedboneschangeinshaw,sizeanddirection,whiletherestoftheskeletonremainsnormal.TheclinicalconsequencesofthediseasewerefirstdescribedbySirJanlesPagetin1876(Figure1).

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简介：31aiscontributiondiscussestheuseofstatins(HMG-CoAreductaseinhibitors),aspirinandantihypertensivedrugsinsecondaryandprimarypreventionofcoronaryheartdisease(CHD),focusingontherationaleforandpracticalaspectsofCI-IDriskassessmentintargetingthesetreatments.