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简介：摘要目的探讨分析长效胰岛素联合口服降糖药治疗新诊断２型糖尿病的临床疗效.方法选取１２０例２型糖尿病患者,随机分为对照组和观察组各６０例,对照组患者采用口服降糖药(二甲双胍和格列美脲)进行治疗,观察组患者在对照组的基础上加用长效胰岛素来得时皮下注射治疗,治疗１２周后观察并记录两组的空腹血糖、餐后２h血糖及糖化血红蛋白(HBA１c).结果１２０例患者治疗后,患者空腹血糖、餐后２h血糖及糖化血红蛋白(HBA１c)均明显下降,观察组的空腹血糖、餐后２h血糖及糖化血红蛋白(HBA１c)下降水平大于对照组,两组差异具有统计学意义(P＜０．０５).结论采用长效胰岛素联合口服降糖药治疗新诊断２型糖尿病,能够及时改善患者血糖指标,维持血糖平衡,提升患者的治疗效果,保障患者的生命健康.关键词长效胰岛素;口服降糖药;２型糖尿病AbstractObjectiveToinvestigatetheclinicalefficacyoflong－actinginsulincombinedwithoralhypoglycemicagentsinpatientswithnewlydiagnosedtype２diabetes．Methodsatotalof１２０patientswithtype２diabetesmellitus,wererandomlydividedascontrolgroupandobservationgroup,eachgrouphad６０cases．Inthecontrolgroupweretreatedwithoralhypoglycemicagents(metforminandglimepiridetreatment,theobservationgrouponthebasisofthecontrolgroupwithlong－actinginsulinLantussubcutaneousinjectiontreatment,１２weeksoftreatment,observeandrecordthetwogroupsoffastingbloodglucose,postprandial２Hbloodglucoseandglycosylatedhemoglobin(HBAincreaseof１inC)．Results１２０casesofpatientsaftertreatment,patientsfastingbloodgluＧcose,postprandial２Hbloodglucoseandglycosylatedhemoglobin(１intheHBAtendingtoc)wereobviouslydecreased．Intheobservationgroup,thefastingbloodglucose,postprandial２hoursbloodglucoseandglycosylatedhemoglobin(１inHbAtendingtoc)declinelevelgreaterthanthecontrolgroup,thedifferencebetweenthetwogroupswithstatisticalsignificance(P＜０．０５)．Conclusionusinglong－actinginsulincombinedwithoralantidiabeticdrugtherapyinnewlydiＧagnosedtype２diabetes,caninatimelymannertoimprovebloodglucosetargets,maintainglucosehomeostasis,andimprovepatientoutcomes,toprotectthepaＧtient＇sKliefyeawnodrdhsealth．Long－actinginsulin;oralhypoglycemicdrugs;type２diabetesmellitus中图分类号R４５３文献标识码B文章编号１００８－６３１５(２０１５)１２－０６８８－０１

简介：摘要目的观察并分析中西医结合治疗糖尿病肾病的临床效果.方法将我院在２０１３年１月到２０１４年１２月收治的１１６例糖尿病肾病患者随机分为观察组和对照组两组,每组５８例.对照组患者单纯采用西医治疗,观察组采用中西医结合治疗,观察并比较两组患者的治疗效果.结果观察组患者的治疗有效率为９４．８３％,对照组的治疗有效率为７２．４１％,P＜０．０５,具有统计学意义;与治疗前相比两组患者的血糖、血脂、肾功能和血液流变学指标均有显著的改善,P＞０．０５,不具有统计学意义;观察组治疗后的血糖、血脂、肾功能和血液流变学指标与对照组相比有较大差异,P＜０．０５,具有统计学意义.结论临床上治疗糖尿病肾病采用中西医结合治疗的效果更为显著,能够提高治疗的有效率,值得在临床上推广使用.关键词中西医结合;糖尿病肾病;治疗中图分类号R５８７．２文献标识码B文章编号１００８－６３１５(２０１５)１０－０３５４－０１