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500 个结果
  • 简介:在thispaper,效果一僵硬在一辆僵硬圆柱的坦克在液体的地震反应上困惑被评估。A困惑是在地面刺激的效果上供应一种被动控制的一个环形的盘子。包含的液体被假定不可压缩,inviscid并且无旋的运动。估计地震反应,模式的重叠的方法被使用了。分析僵硬坦克反应,Laplaces方程被看作液体领域的管理方程,在时间和频率领域。边界元素方法(BEM)被采用在一辆圆柱的坦克评估液体的自然模式。获得这个目标,液体领域被划分成baffle划分的二上面、更低的部分。线性化包含的液体的免费表面的条件被考虑了的运动学、动态的边界。

  • 标签: 地震响应 液体 挡板 动力学边界条件 充填 地震反应
  • 简介:Aprimaryhumanrenalcellcarcinomawasdevelopedasaxenograft(NT-25)andmaintainedbyserialtransplantationinnudemice.TheeffectofUFTonthisneogrowthwastestedandevaluatedaswellitsdistributionintheanimaltissues.TheconcentrationofUFTwashigherintumortissuesthanthatinothertissuesandintheanimalexperimentationUFTwasfoundtobeeffectiveonhumanrenalcellcarcinoma.

  • 标签: NUDE serial maintained ANTITUMOR epithel WEIGHING
  • 简介:Introduction:ARationaleforPeerResponseGroupsPeerresponsegroupshavebecomeacommonsightincompositionclassroomsoverthelasttwentyyears.WhileGere(1987)hasdemonstratedthatpeerresponsegroups,inwhichstudentwritersrespondtooneanother’swriting,havealonganddistinguishedpast,thecurrentuseofsuchgroupsemergedoutofthewidespreadadoptionoftheprocessapproachofthe1960’s,whentheywereadvocatedbyanumberofcompositionpractitioners,includingBruffee(1978;

  • 标签: 伪名
  • 简介:Inthispaper,theSpaceWeatherModelingFramework(SWMF)isusedtosimulatethereal-timeresponseofthemagnetospheretoasolarwindeventonJune5,1998,inwhichtheinterplanetarymagneticfieldshifteditsdirectionfromnorthtosouth.Sincemostcurrentmodelsdonottakeintoaccountconvectiveeffectsoftheinnermagnetosphere,wefirststudytheimportanceofRiceConvectionModel(RCM)intheglobalmodel.Wethenfocusonthefollowingfouraspectsofthemagnetosphere’sresponse:themagnetosphere’sdensitydistribution,thestructureofitsmagneticfieldlines,theareaofthepolarcapboundary,andthecorrespondingionosphericcurrentchange.Wefindthat(1)whentheIMFchangesfromnorthtosouthinthisevent,highmagnetosheathdensityisobservedtoflowdownstreamalongthemagnetopausewiththesolarwind;low-latitudereconnectionatdaysideoccursunderthesouthwardIMF,whilethemagneticfieldlinesinthetaillobecaudal,causedbythenightsidehighlatitudereconnection,extendintotheinterplanetaryspace.Openmagneticfieldlinesexistsimultaneouslyatbothhighandlowlatitudesatthemagnetopause;(2)theareaofthepolarcapisobviouslyincreasediftheIMFturnsfromthenorthtothesouth;thisobservationishighlyconsistentwithempiricalobservations;(3)theionosphericfieldaligncurrentinthenorthernhemisphereisstrongerthaninthesouthernhemisphereandalsoincreasesastheIMFchangesfromnorthtosouth.SWMFwiththeRiceConvectioneffectprovidesreliablemodelingofthemagnetosphericandionosphericresponsetothissolarwindvariation.

  • 标签: MAGNETOSPHERE global MHD simulation POLAR cap
  • 简介:为一个常规短期的设计配方的紧张腿站台(TLP)设计焦点的典型工业实践,它假设N年设计环境导致N年回答。在基于反应的设计方法,TLP被设计承受N年回答而非对N年环境条件作出回应。在这份报纸,我们在场为基于反应的设计方法和使用的概述和一个一般过程比较在二个方法之间的批评TLP回答的案例研究。我们的比较的结果证明常规短期的设计方法经常包含保守主义的一个元素并且基于反应的设计方法能减少设计条件并且从而完成费用积蓄。

  • 标签: 张力腿平台 设计环境 设计方法 TLP 设计条件 成本节约
  • 简介:Thepatternofprecipitation,includingprecipitationamount,frequencyandintensity,maychangeinthefutureaccordingtothepredictionofclimatechange.Inaridzones,thesoildynamics,plantgrowthandvegetationchange,desertificationandhydrologymightbeaffectedbyprecipitationchange.Ingeneral,theprecipitationinextremearidzoneandaridzoneshowedanincreasetendencywhereastheprecipitationinsomeareainsemi-aridzoneandsub-humidaridzoneshowedadecreasetendency.Theincreaseofprecipitationcouldenhancethegrowthofbiologicalsoilcrust,improvesoilwaterstatus,promoteplantgrowth,increasevegetationcoverage,facilitatethechangefromdesertvegetationtograsslandvegetation,anditisbenefittothereversionoflanddesertification.Inaddition,theincreaseofprecipitationcouldalsoincreasetheriverrunoff,lakestorageandpromotetheoccurrenceofflood,whilethedecreaseofprecipitationhastheadverseeffect.Thesestudieswillbenefitthepredictionofthepossibleresponseofecosystemprocessestothepotentialchangeofprecipitationpatterninaridzonesinthefuture,anditisimportanttotheconservationofnaturalvegetationandthecontrolofdesertification.Morefieldexperimentsandstudiesshouldbeconductedinthefuture,includingtheeffectofincreasedprecipitationortemperature,nitrogendepositionandCO2onsoil,vegetation,desertificationandhydrologyofaridzones,soasthemorepersuasiveresultscouldbeobtainedfromtheseexperimentsandstudies.

  • 标签: ARID zone PRECIPITATION CHANGE soil CHANGE
  • 简介:Volterraseriesisapowerfulmathematicaltoolfornonlinearsystemanalysis,andthereisawiderangeofnonlinearengineeringsystemsandstructuresthatcanberepresentedbyaVolterraseriesmodel.Inthepresentstudy,therandomvibrationofnonlinearsystemsisinvestigatedusingVolterraseries.Analyticalexpressionswerederivedforthecalculationoftheoutputpowerspectraldensity(PSD)andinput-outputcross-PSDfornonlinearsystemssubjectedtoGaussianexcitation.Basedontheseexpressions,itwasrevealedthatboththeoutputPSDandtheinput-outputcrossPSDcanbeexpressedaspolynomialfunctionsofthenonlinearcharacteristicparametersortheinputintensity.Numericalstudieswerecarriedouttoverifythetheoreticalanalysisresultandtodemonstratetheeffectivenessofthederivedrelationship.TheresultsreachedinthisstudyareofsignificancetotheanalysisanddesignofthenonlinearengineeringsystemsandstructureswhichcanberepresentedbyaVolterraseriesmodel.

  • 标签: VOLTERRA series Nonlinear system RANDOM vibration
  • 简介:Theerrorperformanceofcontimuonsphasemodulation(CPM)withtheoptimalcoherentdetectiondependsonitsminimumsquaredEuclideandistance(MSED).Inthispaper,areduced-statetrellisforfullresponseCPMispresentedundertheconditionthattheMSEDisnotreduced.andthereforethecomplexityoftheViterbidecodingisroduced.

  • 标签: Continuous phase modulation Optimal COHERENT detection
  • 简介:在意外爆炸景色的调查,玻璃上的损坏是能被用来决定爆炸来源的特征的典型踪迹之一。为了在强风下面分析玻璃的反应,装载,一个数字模型被开发。在模型,易碎物玻璃模特儿被收养。一个节点版本方法,它与侵蚀方法相比有一些特殊优点被用来在计算模仿玻璃的破裂,在玻璃的反应起主要作用的几个问题被讨论。速度和玻璃碎片的排水量是二个主要因素。数字结果对设计和危险评价很有用。

  • 标签: 玻璃窗 爆炸载荷 动力响应 损害
  • 简介:我们建议复杂性的一个新定义。定义看那一个系统什么时候经由一个短暂状态演变到一个最后的状态,它的复杂性两个都取决于许多最后的州、短暂的状态。许多短暂状态可以被对骚乱的反应的差异描述。我们希望这个定义能由证明所有简单系统有零复杂性描述在简单系统和复杂系统之间的一条清楚的边界,并且所有复杂系统有积极复杂性。复杂性计算的一些例子被举,它支持我们的希望。

  • 标签: 干扰作用 最后状态 测量方法 复杂性
  • 简介:意外怪癖是为高大楼的地震设计的一个非标准的假设。考虑它要求地震抵抗的分析,它要求怪癖的结构的自然颤动的也耗时的计算或由为各怪癖的大小写使用一接近的相等的扭力的时刻发现一个静态的排水量答案。这研究建议一条其他的形式的反应光谱分析(MRSA)途径与意外怪癖计算地震回答。建议途径,把瑞利夸耀称为Projection-MRSA(RRP-MRSA),基于MRSA和二策略被开发:获得怪人的近似模式的快计算的一个RRP方法组织的(a);并且(b)装配怪人的集体矩阵的一条途径组织。RRP-MRSA的效率经由设计例子并且与标准MRSA(ST-MRSA)和一个近似方法相比被测试,即,相等的扭力的时刻混血儿MRSA(ETM-MRSA)。数字结果显示出那RRP-MRSA不仅几乎完成象ST-MRSA的一样的精确,并且比ETM-MRSA好一些,但是也是更节俭的。因此,RRP-MRSA能代替在地震设计的当前的意外怪癖计算。

  • 标签: 计算 地震响应 RAYLEIGH 建筑抗震设计 MRSA 偶然偏心
  • 简介:Viscoelasticityandtemperaturecansignificantlyafecttheperformanceofadielectricelastomer.Inthecurrentstudy,weuseathermodynamicmodeltodescribetheefectoftemperatureandviscoelasticityontheelectromechanicalresponseundergoingacyclicelectricloadbytakingintoaccountofthetemperaturedependentdielectricconstant.Becauseofthesignificantviscoelasticityinthedielectricelastomer,thedeformationandthenominalelectricdisplacementcannotkeepinphasewiththeelectricfieldatlowfrequencies.Theresultsshowthatthemagnitudeofthecyclicelectromechanicalactuationstrainincreaseswiththedecreaseofthetemperatureanddecreaseswiththeincreasingfrequency,andviscoelasticitycanresultinsignificanthysteresisfordielectricelastomersunderarelativelowtemperatureandalowfrequency.

  • 标签: 反应温度 粘弹性 弹性体 介电 动态响应 热力学模型
  • 简介:灵活圆形的柱体的导致流动的颤动(FIV)上的集体比率的效果试验性地在一辆拖引的坦克被调查。分别地,有7.9公里和4.8公里的外部、内部的直径的一个Tygon试管为学习被采用。试管被连接到一辆马车并且从休息拖引到一稳定在慢下来在1.6m的距离上再休息在前加快m/s到1.6仍然流水。雷纳兹数字基于柱体,外部直径是80013,000,并且减少的速度(柱体天赋频率使正常化的速度和外部直径)从2~25跨越了。当连接时,柱体在11N的轴的虚荣下面从420公里被伸长到460公里。把伸长的长度基于柱体,方面比率(到外部直径的柱体长度的比率)作为58被计算。三集体比率(柱体的比率结构的质量到代替的液体质量,m*)被分别地用空气,水,和合金粉末(nickel-chromium-boron矩阵合金)填满柱体内部0.7,1.0,和3.4决定。一个光方法为反应大小被采用。多频率颤动在两个被观察同轴(IL)并且跨流动(CF)回答;在高级雷纳兹数字,颤动模式直到3rd在CF反应被识别。模式转变被发现为最高测试的集体比率在更低的减少的速度发生。颤动振幅和频率关于减少的速度被确定并且表示。一个重要减少的颤动振幅与增加集体比率在IL反应被发现,并且仅仅起始、上面的分支在IL和CF反应振幅存在。规范的反应频率被揭示线性地关于减少的速度增加,并且为线性关系的斜坡被发现为测试的三格相同。

  • 标签: 水池试验 质量比 动力响应 圆筒 流体诱导振动 白细胞介素
  • 简介:目的:观察滞针法治疗免疫性不育症的疗效.方法:取肝俞、肾俞、心俞、膈俞、太冲、太溪、神门、血海穴为主,常规刺入穴位后采用滞针法,治疗免疫性不育症79例.结果与结论:经4个月治疗后,总有效率91.1%,且治疗后男性患者精液的精子密度、精子活率、精子活力均有所提高,说明滞针法对免疫性不育症及其异常精液有明显的改善作用.

  • 标签: 不育 免疫性 针刺疗法 滞针
  • 简介:AIM:TOinvestigatetheimmunogenicityofcandidateDNAvaccineagainsthepatitisCvirus(HCV)deliveredbytwoplasmidsexpressingHCVenvelopeprotein1(El)andenvelopeprotein2(E2)antigensrespectivelyandtostudytheeffectofCpGadjuvantonthiscandidatevaccine.METHODS:RecombinantplasmJdsexpressingHCVEIandE2antigensrespectivelywereusedtosimultaneouslyinoculatemicewithorwithoutCpGadjuvant.AntiserawerethencollectedandtJtersofantJ-HCVantibodieswereanalyzedbyELISA.Onemonthafterthelastinjection,animalsweresacrificedtopreparesingle-cellsuspensionofsplenocytes.ThesecellsweresubjectedtoHCVantigenspecificproliferaionassaysandcytokinesecretionassaystoevaluatethecellularimmuneresponsesofthevaccinatedanimals.RESULTS:AntibodyresponsestoHCVEIandE2antigensweredetectedinvaccinatedanimals.AnimalsreceivingCpGadjuvanthadslightlylowertitersofanti-HCVantibodiesinthesera,whilethesplenocytesfromtheseanimalsshowedhigherHCV-antigenspecificproliferation.Analysisofcytokinesecretionfromthesplenocyteswasconsistentwiththeaboveresults.Whilenoantigen-specificIL-4secretionwasdetectedforallvaccinatedanimals,HCVantigen-specificINF-γ,secretionwasdetectedforthesplenocytesofvaccinatedanimals.CpGadjuvantenhancedthesecretionofINF-γ,butdidnotchangetheprofileofIL-4secretion.CONCLUSION:VaccinationofmicewithplasmidsencodingHCVE1andE2antigensinduceshumoralandcellularimmuneresponses.CpGadjuvantsignificantlyenhancesthecellularimmuneresponse.

  • 标签: DNA疫苗 HCV 特效药 体液 细胞免疫反应 抗体
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  • 简介:Thymopentinderivative(septapeptide)waspreparedbymeansofthesolid-phasepeptidesynthesismethodinwhichstepwiseandsegmentcondensationswereinvolved.ThestructuresofthekeyintermediateandtargetmoleculewereconfirmedbyESI-MS,elementaryanalysis,IR,1HNMRand13CNMRspectrometriesinourexperiments.Inthisstudy,theauthorsfoundthatboththymopentinderivetive(septapeptide)andthymopentincouldpromoteTcellproliferationandincreaseofE-rosefomationcells.

  • 标签: 胸腺五肽 免疫调节活性 衍生物 固相合成 电喷雾质谱 T细胞增殖
  • 简介:AccumulatingevidencehasdemonstratedthatregulatoryT(Treg)cellsplayanimportantroleinthemaintenanceofimmunologicself-toleranceandindown-regulatingvariousimmuneresponses.Thus,therehasrecentlybeenanincreasinginterestinstudyingthebiologyofTregcellsaswellastheirpotentialapplicationintreatingimmunediseases.ManytypesofTregcellsubsetshavebeenreportedinavarietyofdiseasemodels.Amongthesesubsets,αβ-TCR+CD3+CD4-CD8-doublenegative(DN)TregcellsaredefinedbytheircapabilityofinhibitingimmuneresponsesviadirectlykillingeffectorTcellsinanantigenspecificfashion.Furthermore,DNTregcellshavebeenshowntodevelopregulatoryactivityafterencounteringspecificantigens,partiallymediatedbytheacquisitionofMHC-peptidecomplexesfromantigenpresentingcells(APCs).ThepresentationofacquiredalloantigensonDNTcellsallowsforthespecificinteractionbetweenDNTregcellsandalloantigenreactiveeffectorTcells.OncetheDNTregandtargetcellshavecomeintocontact,killingisthenmediatedbyFas/Fas-ligandinteractions,andperhapsthroughotherunidentifiedpathways.Furthercharacterizationofthefunctions,molecularexpressionandmechanismsofactivationofDNTregcellswillhelpinthedevelopmentofnoveltherapiestoinduceantigenspecifictolerancetoselfandforeignantigens.Cellular&MolecularImmunology.2004;1(5):328-335.

  • 标签: 双负性调节T细胞 抑制作用 免疫反应 细胞移植 Fas配合体 免疫学