简介:为了精确地在存在水泥模仿氯化物离子的散开,在给定的时间衔接并且获得精确氯化物离子集中,一基于的细胞的自动机(CA)当模特儿被建议。氯化物离子散开的过程被CA-based方法分析,Ficks秒法律的一个非线性的答案被获得。就象压力状态,散开参数的时间、空间的可变性和氯化物离子散开的进程上的水水泥比率那样的各种各样的因素的影响而言,在联合行动的多因素下面的氯化物离子散开的模型被介绍。渗透在文学报导的实验的一个氯化物离子被用来证明现在的方法的有效性和reasonability,并且一根T类型横梁作为一个解说性的例子被拿在实际申请分析氯化物离子散开的过程。结果显示那个CA-based方法能模仿离子实际上与可接受的精确组织的氯化物的散开。
简介:Three-dimensional-printed(3D-P)titaniumimplantsdisplaymanyadvantages,suchasdesignflexibility,higherefficiency,thecapabilitytoeasilyconstructcomplexorcustomizedstructures,etc.,andisbelievedtopotentiallyreplacetraditionalimplants.However,thebiologicalperformanceofthe3D-Ptitaniumsurfacehasnotbeeninvestigatedsystematically.Herein,weanalyzedthesurfacecharacteristicsof3D-PTi6AI4Vimplantsandevaluatedthebiologicalresponsesofbonemarrowderivedmesenchymalstromalcells(BMSCs)tothe3D-Psurfaceinvitro.Moreover,afterimplantationintotheratfemoralcondylefor3and6weeks,theosseointegrationperformaneewasevaluated.Theresultsshowedthe3D-PTi6Al4Vimplantpresenteddistinctfluctuantmacroscaleroughsurfaceandrelativelybetterhydrophilicitywhichenhancedtheadhesion,proliferation,osteogenicdifferentiationandangiogeneticfactorexpressionofBMSCs.Moreover,theinvivoosseointegrationperformancewasalsobetterthanthatofthecontrolgroupattheearlystage.Thepresentstudysuggestedthe3D-Ptitaniumalloyisapromisingcandidatetobeusedasimplantmaterial.