Quantitative Evaluation of Bioluminescence Imaging Based on Radiative Transfer Equation

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摘要 Bioluminescenceimagingisakindofemergingdetectiontechnologyatcellular,molecularandgeneticlevel.Themostpopularbioluminescenceimagingmodelisdiffusionapproximation(DA).However,becauseoftheill-posednessoftheDA-basedinverseproblemandtheinstabilityofreconstructionalgorithms,thelocationaccuracyofthereconstructedsourcesislow.Radiativetransferequation(RTE),whichconsidersthedirectionofthephotonmigrationandtheeffectofabsorptionandscatteringintissues,canaccuratelyexpressthetransmissionofbioluminescentphotonsthroughthetissues.Inthispaper,westudiedthebioluminescenceimagingbasedontheRTE.2Dsimulationswereperformed,andquantitativeevaluationwasgivenbytheabsolutesourcepositionerror,therelativesourceareaerrorandtheminimumboundingbox.TheresultsoftheexperimentshowedthattheimagingqualitybasedonRTEwasbetterthanthatonebasedonDA.
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出版日期 2016年01月11日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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