摘要
摘要目的探究在早发型子痫前期孕妇的临床治疗中解痉抗凝治疗的应用效果.方法选取２００９年６月至２０１４年１２月在我院治疗的早发型子痫前期孕妇２１０例,按照随机分组原则将患者分为对照组和治疗组分别３０例、１８０例,其中对照组患者采取常规的硫酸镁进行治疗,治疗组患者则在硫酸镁常规治疗的基础上采用低分子肝素进行治疗,对比两组患者的妊娠结局以及患者的血压变化情况.结果治疗组患者的胎盘早剥和剖宫产率显著低于对照组;治疗组对应的新生儿窒息和胎儿窘迫病症发生率显著低于对照组新生儿;两组患者在治疗后其血压均有不同程度的下降,同时治疗组下降率相比对照组显著,差异显著具有统计意义(P＜０．０５).结论在早发型子痫前期孕妇的病症控制中解痉抗凝治疗能够显著改善患者的微循环情况,提升母婴分娩质量,值得在临床上推广应用.关键词早发型子痫前期;孕妇;解痉抗凝治疗;临床分析Early－onsetpreeclampsiawomenspasmolysisclinicalanalysisofanticoagulanttherapyAbstractObjectiveToexploretheclinicaltreatmentofearly－onsetpreeclampsiainpregnantwomeninspasmolysisandapplicationeffectofanticoagulanttherapy．SelectionmethodsinJune２００９toDecember２０１４inourhospitaltreatmentofearly－onsetpreeclampsia,２１０casesofpregnantwomen,andinaccordancewiththeprincipleofrandomizedpatientsdividedintocontrolgroupandtreatmentgroup(３０cases,１８０casesrespectively,amongthemthecontrolgrouppatientsadoptconventionalmagnesiumsulfatetreatment,thetreatmentgrouppatientsareinthemagnesiumsulfateonthebasisofroutinetherapywithlowmolecularheparintreatment,comparedtwogroupsofpatientswithpregnancyoutcomes,andthepatient＇sbloodpressurechanges．ResultsthetreatmentgrouppatientswithplacentalabruptionandcesareansectionratewassigＧnificantlylowerthanthecontrolgroup;Treatmentgroupcorrespondstotheincidenceofneonatalasphyxiaandfetaldistresssymptomssignificantlylowerthancontrolgroupinthenewborn;Twogroupsofpatientsaftertreatmentthebloodpressurereducedtosomeextent,atthesametimethantherateoftreatmentgroupdecreasedsignificantly,significantdifferencehasstatisticalsignificance(P＜０．０５)．Conclusionearly－onsetpreeclampsiainpregnantwomenindiseasecontrolspasmolysisanticoagulanttherapycansigKniefyicawnotrldysimprovethemicrocirculationofpatients,improvingthequalityofmaternalandchildbirth,worthyofpopularizationandapplicationinclinic．Eearly－onsetpreeclampsia;Pregnantwomen;Spasmolysisanticoagulanttherapy;Clinicalanalysis中图分类号R７１４．２文献标识码B文章编号１００８－６３１５(２０１５)１０－０４１６－０１
出版日期
2015年09月19日（中国期刊网平台首次上网日期，不代表论文的发表时间）
