摘要
摘要目的探讨H．pylori感染与GERD的关系.方法将GERD患者分为合并和不合并H．pylori感染组,比较两组患者年龄、性别、食管炎发生情况、反流症状计分、焦虑抑郁评分及PPI治疗效果的差异.结果２９．４％的患者合并H．pylori感染.合并H．pylori感染组食管炎发生机率低且程度轻(P＜０．０５),性别、年龄、症状总计分、反酸烧心计分、食管外症状计分、焦虑及抑郁评分以及PPI治疗效果较未合并H．pylori感染组均无显著性差异(P＞０．０５).结论合并H．pylori感染的GERD患者出现食管炎的机率较低且程度较轻,H．pylori感染可能对GERD有一定的保护作用.关键词胃食管反流病;幽门螺杆菌感染;食管炎;反流症状计分AbstractObjectiveToevaluatetherelationshipbetweenH．pyloriinfectionandGERD．MethodsGERDpatientsweredividedintotwogroups(withandwithoutH．pyloriinfection)．Wecomparedthetwogroupswithage,gender,severityofrefluxesophagitis,symptomscores,anxiousanddepressscores,andefficacyofPPItreatment．ResultsThepositiverateofH．pyloriinfectioninallcaseswas２９．４％．ComparedwithnoH．pyloriinfectiongroup,therewaslowerincidenceandseverityofesophagitisinH．pyloriinfectiongroup,(P＜０．０５)．Therewasnodifferencebetweenthetwogroupsintheage,gender,GERDsymptomtotalscores,typicalsympＧtomsscores,morbidityofextra－esophagealsymptoms,thescoresofanxietyanddepression,andefficacyofPPItreatment(P＞０．０５)．ConclusionItshowsthatGERDpatientswithoutH．pyloriinfectionaremorelikelytohaverefluxesophagitisandsevereresophagitis．H．pyloriinfectionmaypayaprotectiveroleinGERD．KeywordsGERD;H．pyloriinfection;Esophagitis;Refluxsymptomsscores中图分类号R５７文献标识码B文章编号１００８－６３１５(２０１５)１０－０３３４－０１
出版日期
2015年09月19日（中国期刊网平台首次上网日期，不代表论文的发表时间）
