Toevaluatetheeffectby“standard/chemotherapywithnavelbine(NVB)pluscisplatin(PDD)inthetreatmentofnonsmallcelllungcancer(NSCLC).”MethodsTherewere40NSCLCpatientsinthisstudy.38weremaleand2female.Themedianageofthepatientswas52yearsold.Squamouscarcinomawasthemostconmontypeofmalignancy(36cases).SixteenpatientswereinthestageⅢaand20patientsinstageⅢb-ⅣTwentypatientshadnopriorchemotherapyand20receivedpreviouschemotherapy.ResultsCompleteresponsewasobservedin4patientsandpartialresponsein15patients.Theoverallresponseratewas47.5%.Theresponserateoftheprimarychemothera-pywas60%.Thesecondarychemotherapywas35%.ThemaintoxityofNVBwasneutropeniawhichwasseeninalltreatedcases(80.5%inGradeⅡandⅢ)Thelocalvenoustoxitywasobservedin35%ofthepatients.ConclusionTheso-calledstandardchemotherapywithNVBplusPDDinthetreatmentofNSCLCmayobtainahigherresponserateandlowertoxity.Itiseffectiveespeciallyforthepatientsofinanearlierstage.
