Analyzing the Biology on the System Level

(整期优先)网络出版时间:2004-01-11
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Althoughvariousgenomeprojectshaveprovidedusenormousstaticsequenceinformation,understandingofthesophisticatedbiologycontinuestorequireintegratingthecomputationalmodeling,systemanalysis,technologydevelopmentforexperiments,andquantitativeexperimentsalltogethertoanalyzethebiologyarchitectureonvariouslevels,whichisjusttheoriginofsystemsbiologysubject.Thisreviewdiscussestheobject,itscharacteristics,andresearchattentionsinsystemsbiology,andsummarizestheanalysismethods,experimentaltechnologies,researchdevelopments,andsooninthefourkeyfieldsofsystemsbiology-systemicstructures,dynamics,controlmethods,anddesignprinciples.